Basic Information
ID: ALA3875325
Type: Binding
Description: Inhibition of Staphylococcus aureus WCUH29 DNA gyrase expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells assessed as inhibition of DNA supercoiling activity using relaxed pBR322 as substrate incubated for 30 mins in presence of ATP by ethidium bromide staining based agarose gel electrophoresis
Format: BAO_0000219
Organism: Staphylococcus aureus
Strain: WCUH29
Target: Unchecked(ALA612545)
Document: ALA3875146
Inhibition of Staphylococcus aureus WCUH29 DNA gyrase expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells assessed as inhibition of DNA supercoiling activity using relaxed pBR322 as substrate incubated for 30 mins in presence of ATP by ethidium bromide staining based agarose gel electrophoresis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3875325
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 188.18 | 1.64 | 1.64 |
| 374.35 | 3.11 | 3.11 |