Basic Information
ID: ALA3875514
Type: Binding
Description: Inhibition of MLL1-WDR5 protein-protein interaction in human MV4-11 cells harboring MLL-AF4 fusion protein assessed as inhibition of Meis-1 gene expression at 2.5 uM after 7 days by RT-PCR method relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MV4-11
Target: Histone-lysine N-methyltransferase 2A/WDR5(ALA3883320)
Document: ALA3875159
Inhibition of MLL1-WDR5 protein-protein interaction in human MV4-11 cells harboring MLL-AF4 fusion protein assessed as inhibition of Meis-1 gene expression at 2.5 uM after 7 days by RT-PCR method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3875514
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 467.98 | 4.62 | 4.62 |