Basic Information
ID: ALA3876024
Type: Binding
Description: Inhibition of human MARK4 expressed in HEK293T cells coexpressing tau protein assessed as reduction in tau phosphorylation at Ser262 residues by AlphaLisa assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-293T
Target: MAP/microtubule affinity-regulating kinase 4(ALA5754)
Document: ALA3875183
Inhibition of human MARK4 expressed in HEK293T cells coexpressing tau protein assessed as reduction in tau phosphorylation at Ser262 residues by AlphaLisa assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3876024
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.39 | 4.18 | 4.18 |
| 324.43 | 3.89 | 3.89 |
| 371.44 | 3.93 | 3.93 |
| 337.43 | 3.57 | 3.57 |
| 311.39 | 3.04 | 3.04 |
| 334.38 | 2.85 | 2.85 |
| 336.44 | 4.18 | 4.18 |
| 385.47 | 4.11 | 4.11 |
| 322.46 | 4.65 | 4.65 |
| 377.42 | 4.14 | 4.14 |
| 375.43 | 3.71 | 3.71 |
| 386.45 | 4.24 | 4.24 |
| 463.56 | 3.90 | 3.90 |
| 420.56 | 3.59 | 3.59 |
| 359.43 | 4.00 | 4.00 |
| 373.46 | 4.17 | 4.17 |
| 394.43 | 4.85 | 4.85 |
| 254.29 | 2.45 | 2.45 |