Basic Information
ID: ALA3876413
Type: Binding
Description: Antagonist activity at SRA in RM1-OVA tumor bearing wild type C57BL/6 mouse derived CD11bpositiveLy6ChighLy6Gnegative myeloid-derived suppressive cells co-cultured with splenocytes assessed as reduction in protein-mediated inhibition of anti CD3/CD28 antibody-induced T-cell activation by measuring IL-2 secretion at 10 to 20 uM pretreated for 2 hrs followed by splenocytes addition measured after 56 hrs by ELISA
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA3876413
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 268.22 | 1.87 | 1.87 |