Basic Information
ID: ALA3876414
Type: Binding
Description: Antagonist activity at SRA in RM1-OVA tumor bearing wild type C57BL/6 mouse derived CD11bpositiveLy6ChighLy6Gnegative myeloid-derived suppressive cells co-cultured with splenocytes assessed as reduction in protein-mediated inhibition of anti CD3/CD28 antibody-induced T-cell proliferation at 10 to 20 uM preincubated for 2 hrs followed by splenocytes addition measured after 72 hrs by [3H]-thymidine incorporation assay
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA3876414
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.22 | 1.57 | 1.57 |
| 240.21 | 1.87 | 1.87 |
| 268.22 | 1.87 | 1.87 |