Agonist activity at recombinant human S1PR5 expressed in CHO cell membranes assessed as [35S]GTP-gammaS binding measured after 1.5 hrs by TopCount sci...

Basic Information

ID: ALA3876448

Type: Binding

Description: Agonist activity at recombinant human S1PR5 expressed in CHO cell membranes assessed as [35S]GTP-gammaS binding measured after 1.5 hrs by TopCount scintillation counting method

Format: BAO_0000219

Organism: Homo sapiens

Cell type: CHO

Target: Sphingosine 1-phosphate receptor Edg-8(ALA2274)

Document: ALA3875189

Agonist activity at recombinant human S1PR5 expressed in CHO cell membranes assessed as [35S]GTP-gammaS binding measured after 1.5 hrs by TopCount scintillation counting method: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3876448

EC50

Total(61)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
375.49	5.68	5.68
401.53	6.37	6.37
353.49	4.94	4.94
353.49	5.09	5.09
347.44	4.90	4.90
361.47	5.29	5.29
376.48	4.22	4.22
423.54	6.96	6.96
401.53	6.12	6.12
353.49	4.94	4.94
389.52	6.07	6.07
389.52	6.07	6.07
373.48	5.24	5.24
373.48	5.24	5.24
389.52	6.07	6.07
351.47	4.65	4.65
423.54	6.96	6.96
423.54	6.71	6.71
361.47	5.29	5.29
369.44	4.25	4.25
361.47	5.29	5.29
423.54	6.96	6.96
401.53	6.37	6.37
423.54	6.71	6.71
375.49	5.68	5.68
367.51	5.48	5.48
393.43	5.54	5.54
423.54	6.96	6.96
339.46	4.83	4.83
375.49	5.53	5.53
339.46	4.70	4.70
376.48	4.22	4.22
423.54	6.96	6.96
423.54	6.96	6.96
325.43	4.30	4.30
401.53	6.19	6.19
325.43	4.30	4.30
393.43	5.54	5.54
401.53	6.19	6.19
354.48	3.63	3.63
381.54	5.82	5.82
423.54	6.71	6.71
373.48	5.24	5.24
375.49	5.68	5.68
375.49	5.53	5.53
339.46	4.70	4.70
351.47	4.65	4.65
401.53	6.12	6.12
376.48	4.22	4.22
339.46	4.83	4.83
367.51	5.48	5.48
401.53	6.37	6.37
354.48	3.63	3.63
375.49	5.53	5.53
347.44	4.90	4.90
375.49	5.68	5.68
405.52	5.68	5.68
339.46	4.83	4.83
401.53	6.37	6.37
347.44	4.90	4.90
353.49	5.09	5.09