Basic Information
ID: ALA3876453
Type: ADME
Description: Agonist activity at recombinant human S1PR3 expressed in CHO cell membranes assessed as [35S]GTP-gammaS binding measured after 1.5 hrs by TopCount scintillation counting method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Sphingosine 1-phosphate receptor Edg-3(ALA3892)
Document: ALA3875189
Agonist activity at recombinant human S1PR3 expressed in CHO cell membranes assessed as [35S]GTP-gammaS binding measured after 1.5 hrs by TopCount scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3876453
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 375.49 | 5.68 | 5.68 |
| 401.53 | 6.37 | 6.37 |
| 353.49 | 4.94 | 4.94 |
| 353.49 | 5.09 | 5.09 |
| 347.44 | 4.90 | 4.90 |
| 361.47 | 5.29 | 5.29 |
| 376.48 | 4.22 | 4.22 |
| 423.54 | 6.96 | 6.96 |
| 401.53 | 6.12 | 6.12 |
| 353.49 | 4.94 | 4.94 |
| 389.52 | 6.07 | 6.07 |
| 389.52 | 6.07 | 6.07 |
| 373.48 | 5.24 | 5.24 |
| 373.48 | 5.24 | 5.24 |
| 389.52 | 6.07 | 6.07 |
| 351.47 | 4.65 | 4.65 |
| 423.54 | 6.96 | 6.96 |
| 423.54 | 6.71 | 6.71 |
| 361.47 | 5.29 | 5.29 |
| 361.47 | 5.29 | 5.29 |
| 423.54 | 6.96 | 6.96 |
| 401.53 | 6.37 | 6.37 |
| 423.54 | 6.71 | 6.71 |
| 375.49 | 5.68 | 5.68 |
| 367.51 | 5.48 | 5.48 |
| 423.54 | 6.96 | 6.96 |
| 375.49 | 5.53 | 5.53 |
| 339.46 | 4.70 | 4.70 |
| 376.48 | 4.22 | 4.22 |
| 423.54 | 6.96 | 6.96 |
| 423.54 | 6.96 | 6.96 |
| 325.43 | 4.30 | 4.30 |
| 325.43 | 4.30 | 4.30 |
| 354.48 | 3.63 | 3.63 |
| 423.54 | 6.71 | 6.71 |
| 373.48 | 5.24 | 5.24 |
| 375.49 | 5.53 | 5.53 |
| 339.46 | 4.70 | 4.70 |
| 351.47 | 4.65 | 4.65 |
| 401.53 | 6.12 | 6.12 |
| 376.48 | 4.22 | 4.22 |
| 367.51 | 5.48 | 5.48 |
| 401.53 | 6.37 | 6.37 |
| 354.48 | 3.63 | 3.63 |
| 375.49 | 5.53 | 5.53 |
| 347.44 | 4.90 | 4.90 |
| 375.49 | 5.68 | 5.68 |
| 401.53 | 6.37 | 6.37 |
| 347.44 | 4.90 | 4.90 |
| 353.49 | 5.09 | 5.09 |