Basic Information
ID: ALA3877553
Type: Binding
Description: Antagonist activity at human alpha4beta2 expressed in human SH-EP1 cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated for 10 mins followed by carbamylcholine addition measured after 5 mins by Cherenkov counting
Organism: Homo sapiens
Cell type: SH-EP1
Activity Charts
Bioactivity
Activity Types for Assay ALA3877553
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 289.42 | 2.36 | 2.36 |
| 275.40 | 2.02 | 2.02 |
| 273.38 | 1.77 | 1.77 |
| 302.38 | 1.41 | 1.41 |
| 273.38 | 1.77 | 1.77 |
| 275.40 | 2.02 | 2.02 |
| 288.35 | 1.07 | 1.07 |