Basic Information
ID: ALA3877710
Type: Binding
Description: Inhibition of mouse GAT2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition measured after 10 mins by liquid scintillation counter method
Format: BAO_0000219
Organism: Mus musculus
Cell type: HEK293
Target: GABA transporter 2(ALA4228)
Document: ALA3877251
Inhibition of mouse GAT2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition measured after 10 mins by liquid scintillation counter method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3877710
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 140.14 | 0.43 | 0.43 |
| 346.43 | 4.42 | 4.42 |
| 436.51 | 5.39 | 5.39 |
| 480.56 | 5.45 | 5.45 |
| 482.58 | 5.68 | 5.68 |
| 494.59 | 6.15 | 6.15 |
| 482.58 | 5.68 | 5.68 |
| 480.56 | 5.45 | 5.45 |
| 450.54 | 5.48 | 5.48 |
| 496.61 | 6.07 | 6.07 |
| 468.55 | 5.29 | 5.29 |
| 494.59 | 5.50 | 5.50 |
| 468.55 | 5.29 | 5.29 |
| 454.53 | 4.90 | 4.90 |