Basic Information
ID: ALA3877721
Type: Binding
Description: Inhibition of mouse GAT2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake at 100 uM preincubated for 25 mins followed by [3H]GABA addition measured after 10 mins by liquid scintillation counter method
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3877721
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.54 | 4.78 | 4.78 |
| 375.56 | 5.04 | 5.04 |
| 138.13 | 0.51 | 0.51 |
| 436.51 | 5.39 | 5.39 |
| 454.53 | 4.90 | 4.90 |
| 516.59 | 4.93 | 4.93 |
| 454.53 | 4.90 | 4.90 |
| 440.50 | 4.51 | 4.51 |
| 498.58 | 4.91 | 4.91 |
| 482.58 | 5.68 | 5.68 |
| 468.55 | 5.29 | 5.29 |
| 440.50 | 4.51 | 4.51 |