Basic Information
ID: ALA3877723
Type: Binding
Description: Inhibition of mouse GAT4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake at 100 uM preincubated for 25 mins followed by [3H]GABA addition measured after 4 mins by liquid scintillation counter method
Format: BAO_0000219
Organism: Mus musculus
Cell type: HEK293
Target: GABA transporter 4(ALA3699)
Document: ALA3877251
Inhibition of mouse GAT4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake at 100 uM preincubated for 25 mins followed by [3H]GABA addition measured after 4 mins by liquid scintillation counter method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3877723
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 375.56 | 5.04 | 5.04 |
| 138.13 | 0.51 | 0.51 |
| 346.43 | 4.42 | 4.42 |
| 454.53 | 4.90 | 4.90 |
| 454.53 | 4.90 | 4.90 |
| 480.56 | 5.45 | 5.45 |
| 440.50 | 4.51 | 4.51 |
| 498.58 | 4.91 | 4.91 |
| 482.58 | 5.68 | 5.68 |
| 468.55 | 5.29 | 5.29 |
| 440.50 | 4.51 | 4.51 |
| 468.55 | 5.29 | 5.29 |
| 454.53 | 4.90 | 4.90 |