Basic Information
ID: ALA3877873
Type: Binding
Description: Inhibition of recombinant human CYP1B1 expressed in bacterial microsomes co-expressing P450 reductase at 3 uM using 7-ethyl-O-resorufin as substrate after 45 mins in presence of NADPH by fluorescence assay relative to control
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3877873
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.30 | 4.61 | 4.61 |
| 302.41 | 3.62 | 3.62 |
| 290.45 | 3.96 | 3.96 |
| 349.45 | 2.69 | 2.69 |
| 381.49 | 2.49 | 2.49 |
| 300.40 | 3.83 | 3.83 |
| 270.37 | 3.82 | 3.82 |
| 286.37 | 3.25 | 3.25 |
| 286.42 | 3.92 | 3.92 |
| 326.44 | 4.32 | 4.32 |
| 284.40 | 4.12 | 4.12 |
| 290.38 | 3.75 | 3.75 |
| 290.38 | 3.75 | 3.75 |
| 393.37 | 5.01 | 5.01 |
| 430.18 | 5.13 | 5.13 |
| 254.37 | 4.11 | 4.11 |
| 351.28 | 4.37 | 4.37 |
| 313.40 | 3.57 | 3.57 |
| 351.28 | 4.37 | 4.37 |
| 374.43 | 3.09 | 3.09 |
| 471.62 | 4.11 | 4.11 |
| 375.31 | 4.38 | 4.38 |
| 296.41 | 4.18 | 4.18 |
| 397.60 | 6.05 | 6.05 |
| 720.98 | 4.70 | 4.70 |
| 469.67 | 5.60 | 5.60 |
| 421.54 | 4.31 | 4.31 |
| 673.88 | 4.58 | 4.58 |
| 313.44 | 4.18 | 4.18 |
| 362.38 | 3.43 | 3.43 |
| 421.54 | 4.16 | 4.16 |
| 268.36 | 3.75 | 3.75 |
| 392.54 | 5.23 | 5.23 |
| 375.31 | 4.38 | 4.38 |
| 623.82 | 3.84 | 3.84 |
| 272.39 | 3.39 | 3.39 |
| 313.40 | 4.20 | 4.20 |
| 411.63 | 6.35 | 6.35 |
| 594.80 | 5.70 | 5.70 |
| 269.39 | 3.69 | 3.69 |
| 298.38 | 3.81 | 3.81 |
| 379.34 | 4.68 | 4.68 |
| 286.44 | 4.40 | 4.40 |
| 282.43 | 4.67 | 4.67 |
| 684.96 | 8.36 | 8.36 |
| 472.59 | 1.80 | 1.80 |
| 362.49 | 3.84 | 3.84 |
| 383.62 | 6.48 | 6.48 |