Basic Information
ID: ALA3878760
Type: Binding
Description: Inhibition of TSPO in mouse HT22 cells assessed as protection against amyloid beta (1 to 42)-induced mitochondrial membrane potential loss by measuring recovery of ATP production at 5 uM preincubated for 10 mins followed by amyloid beta (1 to 42) addition measured after 7 hrs by luciferase reporter gene assay relative to control
Organism: Mus musculus
Cell type: HT-22
Activity Charts
Bioactivity
Activity Types for Assay ALA3878760
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 142.16 | -0.91 | -0.91 |
| 1202.63 | ||
| 383.50 | 5.77 | 5.77 |
| 452.39 | 7.08 | 7.08 |
| 486.83 | 7.73 | 7.73 |
| 513.68 | 6.88 | 6.88 |
| 470.36 | 5.59 | 5.59 |
| 521.49 | 6.20 | 6.20 |
| 521.49 | 6.20 | 6.20 |
| 521.49 | 6.20 | 6.20 |
| 397.52 | 5.95 | 5.95 |
| 525.70 | 5.38 | 5.38 |
| 414.55 | 5.50 | 5.50 |
| 535.52 | 6.59 | 6.59 |
| 465.17 | 6.96 | 6.96 |
| 399.54 | 5.12 | 5.12 |
| 486.83 | 7.73 | 7.73 |
| 457.57 | 5.71 | 5.71 |
| 537.49 | 5.43 | 5.43 |
| 495.45 | 5.66 | 5.66 |
| 466.41 | 7.00 | 7.00 |
| 507.47 | 5.81 | 5.81 |
| 565.76 | 6.30 | 6.30 |
| 439.60 | 6.94 | 6.94 |
| 393.85 | 5.52 | 5.52 |