Assay Report Card

Basic Information

ID: ALA3878763

Type: Binding

Description: Inhibition of TSPO in mouse HT22 cells assessed as inhibition of amyloid beta (1 to 42)-induced ROS generation at 5 uM after 6 hrs by DCFDA staining based fluorescence assay relative to control

Organism: Mus musculus

Cell type: HT-22

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
142.16-0.91-0.91
513.686.886.88
470.365.595.59
521.496.206.20
521.496.206.20
397.525.955.95
535.526.596.59
486.837.737.73
495.455.665.66
466.417.007.00