Basic Information
ID: ALA3878768
Type: ADME
Description: Inhibition of recombinant human CYP2C19 expressed in baculosomes coexpressing rabbit NADPH-P450 reudctase assessed as residual activity at 10 uM preincubated for 5 mins followed by substrate and NADP+ addition measured after 20 mins by fluorescence assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3878768
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.68 | 6.88 | 6.88 |
| 521.49 | 6.20 | 6.20 |
| 535.52 | 6.59 | 6.59 |
| 486.83 | 7.73 | 7.73 |
| 495.45 | 5.66 | 5.66 |
| 466.41 | 7.00 | 7.00 |