Assay Report Card

Basic Information

ID: ALA3878790

Type: Binding

Description: Inhibition of TSPO in mouse HT22 cells assessed as inhibition of amyloid beta (1 to 42)-induced mitochondrial permeability transition pore opening by measuring decrease in intracellular calcium level after 30 mins by Fura-2-AM dye based fluorescence assay

Organism: Mus musculus

Cell type: HT-22

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
352.875.435.43
466.417.007.00