Basic Information
ID: ALA3878926
Type: ADME
Description: Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins followed by addition of acetylcholine measured for 2 mins by Fluo-4AM dye based FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3878926
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 258.32 | 1.34 | 1.34 |
| 258.32 | 1.15 | 1.15 |
| 258.32 | 1.34 | 1.34 |
| 264.35 | 1.41 | 1.41 |
| 334.42 | 3.01 | 3.01 |
| 308.39 | 2.50 | 2.50 |
| 374.47 | 2.58 | 2.58 |
| 308.39 | 2.50 | 2.50 |
| 300.39 | 2.17 | 2.17 |
| 344.44 | 2.57 | 2.57 |
| 334.42 | 3.01 | 3.01 |
| 348.86 | 3.21 | 3.21 |
| 258.32 | 1.34 | 1.34 |
| 358.47 | 2.96 | 2.96 |
| 314.41 | 2.56 | 2.56 |
| 314.41 | 2.56 | 2.56 |
| 344.44 | 2.57 | 2.57 |
| 340.45 | 3.07 | 3.07 |
| 314.41 | 2.56 | 2.56 |
| 300.39 | 2.17 | 2.17 |
| 344.44 | 2.57 | 2.57 |
| 330.41 | 2.26 | 2.26 |
| 314.41 | 2.56 | 2.56 |
| 358.47 | 2.72 | 2.72 |
| 344.44 | 2.57 | 2.57 |
| 344.44 | 2.57 | 2.57 |
| 314.41 | 2.56 | 2.56 |
| 328.44 | 2.87 | 2.87 |
| 257.34 | 1.95 | 1.95 |
| 340.45 | 3.07 | 3.07 |
| 358.47 | 2.96 | 2.96 |
| 344.44 | 2.57 | 2.57 |
| 314.41 | 2.56 | 2.56 |
| 308.39 | 2.50 | 2.50 |