Basic Information
ID: ALA3879300
Type: Binding
Description: Inhibition of Rickettsia prowazekii str. Madrid E N-terminal His-tagged methionine aminopeptidase 1A expressed in Escherichia coli BL21(DE3) Rosetta cells using Met-AMC as substrate preincubated for 1 hr followed by substrate addition measured after 30 mins for 90 mins in presence of MnCl2 by fluorescence assay
Organism: Rickettsia prowazekii str. Madrid E
Activity Charts
Bioactivity
Activity Types for Assay ALA3879300
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 145.16 | 1.94 | 1.94 |
| 159.19 | 2.25 | 2.25 |
| 257.07 | 3.95 | 3.95 |
| 188.18 | 2.64 | 2.64 |
| 222.63 | 3.30 | 3.30 |
| 256.18 | 3.66 | 3.66 |
| 179.61 | 2.59 | 2.59 |
| 224.26 | 1.82 | 1.82 |
| 220.30 | 1.99 | 1.99 |
| 275.16 | 2.99 | 2.99 |
| 206.27 | 1.68 | 1.68 |
| 240.72 | 2.33 | 2.33 |
| 233.18 | 2.55 | 2.55 |
| 190.16 | 1.85 | 1.85 |
| 248.35 | 2.80 | 2.80 |
| 262.38 | 2.98 | 2.98 |
| 278.74 | 2.43 | 2.43 |
| 287.32 | 2.83 | 2.83 |
| 289.29 | 1.68 | 1.68 |
| 202.21 | 2.95 | 2.95 |
| 267.08 | 3.41 | 3.41 |
| 256.18 | 3.66 | 3.66 |
| 240.72 | 2.33 | 2.33 |
| 204.25 | 3.11 | 3.11 |
| 202.21 | 2.95 | 2.95 |
| 202.21 | 2.95 | 2.95 |