Basic Information
ID: ALA3880020
Type: Binding
Description: Inhibition of human TRPM5 transfected in HEK293 cells assessed as inhibition of ATP-mediated calcium mobilization by Calcium3 dye-based FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3880020
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.41 | 2.95 | 2.95 |
| 384.48 | 4.66 | 4.66 |
| 386.46 | 4.05 | 4.05 |
| 357.42 | 3.43 | 3.43 |
| 360.42 | 3.20 | 3.20 |
| 377.44 | 3.65 | 3.65 |
| 401.47 | 3.92 | 3.92 |
| 357.42 | 3.43 | 3.43 |
| 400.48 | 4.36 | 4.36 |
| 360.44 | 2.44 | 2.44 |
| 391.47 | 3.96 | 3.96 |
| 350.81 | 3.54 | 3.54 |
| 363.42 | 3.33 | 3.33 |
| 456.55 | 4.78 | 4.78 |
| 356.43 | 4.04 | 4.04 |
| 365.43 | 3.51 | 3.51 |
| 392.38 | 3.98 | 3.98 |
| 457.53 | 4.18 | 4.18 |
| 395.46 | 3.52 | 3.52 |
| 379.46 | 3.82 | 3.82 |
| 348.41 | 3.03 | 3.03 |
| 400.48 | 4.36 | 4.36 |
| 366.42 | 2.90 | 2.90 |
| 351.41 | 3.20 | 3.20 |
| 370.46 | 4.35 | 4.35 |
| 360.42 | 3.20 | 3.20 |
| 364.84 | 3.85 | 3.85 |
| 370.46 | 4.35 | 4.35 |
| 329.40 | 3.80 | 3.80 |
| 399.88 | 4.16 | 4.16 |
| 369.88 | 4.44 | 4.44 |
| 329.40 | 3.80 | 3.80 |
| 395.46 | 3.00 | 3.00 |
| 370.46 | 4.12 | 4.12 |
| 358.41 | 2.83 | 2.83 |
| 345.40 | 3.50 | 3.50 |
| 379.87 | 3.38 | 3.38 |
| 384.27 | 4.80 | 4.80 |
| 413.91 | 4.47 | 4.47 |
| 363.85 | 4.45 | 4.45 |
| 327.38 | 2.58 | 2.58 |
| 365.43 | 3.51 | 3.51 |
| 366.42 | 2.90 | 2.90 |
| 364.85 | 3.60 | 3.60 |
| 347.39 | 3.94 | 3.94 |
| 442.95 | 3.91 | 3.91 |
| 379.46 | 3.59 | 3.59 |
| 383.37 | 4.51 | 4.51 |
| 379.85 | 4.15 | 4.15 |
| 457.53 | 4.18 | 4.18 |
| 370.46 | 4.35 | 4.35 |
| 349.82 | 4.14 | 4.14 |
| 338.41 | 3.30 | 3.30 |
| 456.55 | 4.78 | 4.78 |
| 365.43 | 3.28 | 3.28 |
| 370.46 | 4.35 | 4.35 |
| 376.46 | 3.32 | 3.32 |
| 333.37 | 3.63 | 3.63 |
| 356.43 | 4.04 | 4.04 |
| 455.56 | 5.39 | 5.39 |
| 410.88 | 2.67 | 2.67 |
| 456.55 | 4.78 | 4.78 |
| 409.49 | 3.26 | 3.26 |
| 339.40 | 2.66 | 2.66 |
| 378.88 | 3.99 | 3.99 |
| 361.83 | 3.23 | 3.23 |
| 375.43 | 3.51 | 3.51 |
| 397.45 | 3.95 | 3.95 |