Basic Information
ID: ALA3880038
Type: Binding
Description: Inhibition of Crm1 in human U2OS cells expressing GFP-fused HIV1 Rev assessed as decrease in nuclear export of GFP-fused HIV1 Rev after 1 hr by Hoechst 33258 staining-based assay
Organism: Homo sapiens
Cell type: U2OS
Activity Charts
Bioactivity
Activity Types for Assay ALA3880038
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 304.74 | 1.58 | 1.58 |
| 305.72 | 2.01 | 2.01 |
| 321.76 | 3.03 | 3.03 |
| 321.76 | 3.03 | 3.03 |
| 305.77 | 3.11 | 3.11 |
| 365.82 | 3.05 | 3.05 |
| 305.77 | 3.11 | 3.11 |
| 305.76 | 3.41 | 3.41 |
| 453.42 | 4.23 | 4.23 |
| 355.32 | 3.39 | 3.39 |
| 332.79 | 2.36 | 2.36 |
| 303.75 | 3.16 | 3.16 |
| 277.71 | 2.63 | 2.63 |
| 279.25 | 2.26 | 2.26 |
| 320.78 | 3.06 | 3.06 |
| 295.70 | 2.77 | 2.77 |
| 333.78 | 2.79 | 2.79 |
| 438.45 | 3.86 | 3.86 |
| 283.74 | 2.07 | 2.07 |
| 319.75 | 2.40 | 2.40 |
| 230.66 | 2.59 | 2.59 |
| 412.41 | 3.33 | 3.33 |
| 291.74 | 3.02 | 3.02 |
| 230.66 | 2.59 | 2.59 |
| 273.64 | 3.63 | 3.63 |
| 326.18 | 3.74 | 3.74 |
| 292.73 | 2.42 | 2.42 |
| 395.39 | 3.75 | 3.75 |
| 324.77 | 3.78 | 3.78 |
| 329.75 | 2.54 | 2.54 |
| 325.75 | 3.67 | 3.67 |
| 343.21 | 2.59 | 2.59 |
| 340.38 | 3.03 | 3.03 |
| 307.74 | 2.64 | 2.64 |
| 306.75 | 2.60 | 2.60 |
| 316.79 | 3.13 | 3.13 |
| 305.77 | 3.41 | 3.41 |
| 298.75 | 2.48 | 2.48 |
| 340.17 | 1.63 | 1.63 |
| 267.74 | 2.41 | 2.41 |
| 333.73 | 1.93 | 1.93 |
| 432.40 | 4.36 | 4.36 |
| 350.81 | 3.20 | 3.20 |
| 383.37 | 3.60 | 3.60 |
| 331.80 | 3.95 | 3.95 |
| 288.74 | 2.30 | 2.30 |
| 291.74 | 3.02 | 3.02 |
| 439.90 | 5.05 | 5.05 |
| 322.75 | 2.42 | 2.42 |
| 304.74 | 1.58 | 1.58 |
| 354.80 | 3.72 | 3.72 |
| 384.36 | 3.57 | 3.57 |
| 317.35 | 2.38 | 2.38 |
| 321.76 | 3.03 | 3.03 |
| 327.17 | 3.07 | 3.07 |
| 340.77 | 3.21 | 3.21 |
| 403.38 | 2.79 | 2.79 |
| 351.38 | 4.17 | 4.17 |
| 418.28 | 5.47 | 5.47 |
| 291.74 | 3.02 | 3.02 |
| 338.80 | 3.80 | 3.80 |
| 349.82 | 3.24 | 3.24 |
| 275.28 | 2.58 | 2.58 |
| 304.78 | 3.01 | 3.01 |
| 277.71 | 2.63 | 2.63 |
| 375.73 | 3.92 | 3.92 |
| 339.79 | 3.29 | 3.29 |
| 326.18 | 3.67 | 3.67 |
| 325.29 | 3.39 | 3.39 |
| 383.84 | 4.81 | 4.81 |
| 383.37 | 4.17 | 4.17 |
| 322.29 | 3.75 | 3.75 |
| 271.32 | 2.68 | 2.68 |
| 293.71 | 2.25 | 2.25 |
| 412.41 | 3.33 | 3.33 |
| 438.45 | 3.86 | 3.86 |
| 312.16 | 3.29 | 3.29 |
| 359.22 | 4.36 | 4.36 |
| 317.78 | 3.56 | 3.56 |
| 297.77 | 3.08 | 3.08 |
| 368.32 | 1.96 | 1.96 |
| 433.39 | 3.76 | 3.76 |
| 291.74 | 3.09 | 3.09 |
| 349.82 | 3.81 | 3.81 |