Basic Information
ID: ALA3880074
Type: Binding
Description: Inhibition of Crm1 in human H929 cells assessed as decrease in nuclear export of topoisomerase-2 by measuring caspase-3 levels at 0.1 to 10 uM preincubated for 16 hrs followed by addition of topoisomerase-2 inhibitor doxorubicin measured after 4 hrs by anti-caspase-3 assay
Organism: Homo sapiens
Cell type: H929
Activity Charts
Bioactivity
Activity Types for Assay ALA3880074
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 291.74 | 3.02 | 3.02 |