Assay Report Card

Basic Information

ID: ALA3880111

Type: Binding

Description: Inhibition of recombinant human acid sphingomyelinase expressed in HEKfreestyle293 cells using bodipy-C12 sphingomyelin as substrate and nanomolar to low micromolar concentration of compound after 1 hr by fluorescence assay

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA3880111

Inhibition

Total(63)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
637.65	10.30	10.30
535.67	5.53	5.53
467.50	5.76	5.76
601.67	9.68	9.68
481.53	6.15	6.15
509.58	7.07	7.07
509.58	7.19	7.19
565.69	9.15	9.15
531.54	7.57	7.57
509.58	7.07	7.07
545.56	7.60	7.60
481.53	6.15	6.15
587.64	9.29	9.29
537.64	8.24	8.24
536.65	6.50	6.50
509.58	7.07	7.07
573.62	9.27	9.27
425.47	4.84	4.84
581.54	8.21	8.21
383.34	3.99	3.99
601.67	9.68	9.68
495.56	7.02	7.02
559.59	8.62	8.62
587.64	9.66	9.66
615.70	10.07	10.07
495.56	7.02	7.02
523.61	7.80	7.80
587.64	9.66	9.66
587.64	9.66	9.66
709.82	9.29	9.29
609.60	9.25	9.25
531.54	7.57	7.57
581.54	8.21	8.21
531.54	7.57	7.57
651.68	10.69	10.69
545.56	7.60	7.60
537.64	8.24	8.24
509.58	7.19	7.19
397.37	4.29	4.29
551.66	9.11	9.11
595.67	7.72	7.72
537.64	8.24	8.24
451.50	6.41	6.41
495.56	7.02	7.02
473.47	5.86	5.86
481.53	6.15	6.15
601.67	9.68	9.68
545.56	7.60	7.60
587.64	9.29	9.29
637.65	10.30	10.30
565.69	9.02	9.02
367.34	4.28	4.28
565.69	9.15	9.15
523.61	8.07	8.07
439.45	5.46	5.46
559.59	8.62	8.62
587.64	9.29	9.29
637.65	10.30	10.30
565.69	9.15	9.15
573.62	8.64	8.64
509.58	7.19	7.19
581.54	8.21	8.21
559.59	8.62	8.62