Basic Information
ID: ALA3880148
Type: Binding
Description: Inhibition of A-Raf (unknown origin) assessed as decrease in biotin-tagged MEK1 phosphorylation after 45 mins
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3880148
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 439.40 | 3.14 | 3.14 |
| 474.39 | 4.02 | 4.02 |
| 599.66 | 4.39 | 4.39 |
| 483.83 | 4.80 | 4.80 |
| 498.56 | 5.24 | 5.24 |
| 465.84 | 4.67 | 4.67 |
| 461.42 | 4.02 | 4.02 |
| 499.50 | 3.38 | 3.38 |
| 438.42 | 3.74 | 3.74 |
| 585.63 | 4.00 | 4.00 |
| 469.50 | 3.55 | 3.55 |
| 483.83 | 4.80 | 4.80 |
| 525.58 | 4.89 | 4.89 |
| 482.54 | 3.61 | 3.61 |
| 474.39 | 4.02 | 4.02 |
| 420.43 | 3.61 | 3.61 |
| 456.40 | 3.88 | 3.88 |
| 445.42 | 4.32 | 4.32 |
| 583.66 | 5.15 | 5.15 |
| 456.40 | 3.88 | 3.88 |
| 500.53 | 3.75 | 3.75 |
| 447.46 | 3.22 | 3.22 |
| 403.41 | 3.21 | 3.21 |
| 445.42 | 4.32 | 4.32 |
| 479.41 | 4.16 | 4.16 |
| 479.41 | 4.16 | 4.16 |
| 569.63 | 4.76 | 4.76 |
| 472.47 | 3.99 | 3.99 |
| 448.84 | 3.92 | 3.92 |
| 428.42 | 3.58 | 3.58 |
| 548.59 | 4.26 | 4.26 |
| 456.40 | 3.88 | 3.88 |
| 465.84 | 4.67 | 4.67 |
| 463.41 | 4.46 | 4.46 |