ID: ALA3880154
Type: Functional
Description: Cytotoxicity against human COLO205 cells expressing B-RAF V600E mutant assessed as growth inhibition after 3 days by ATPlite 1 step luminescence assay
Organism: Homo sapiens
Cell type: COLO 205
Bioactivity
Activity Types for Assay ALA3880154
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
448.84 | 3.92 | 3.92 |
539.50 | 4.48 | 4.48 |
599.66 | 4.39 | 4.39 |
483.83 | 4.80 | 4.80 |
471.49 | 3.87 | 3.87 |
498.56 | 5.24 | 5.24 |
471.49 | 3.99 | 3.99 |
465.84 | 4.67 | 4.67 |
547.61 | 4.68 | 4.68 |
461.42 | 4.02 | 4.02 |
513.53 | 4.24 | 4.24 |
548.59 | 3.80 | 3.80 |
463.41 | 4.46 | 4.46 |
557.49 | 4.62 | 4.62 |
574.63 | 4.33 | 4.33 |
473.51 | 3.87 | 3.87 |
499.50 | 3.38 | 3.38 |
490.92 | 4.94 | 4.94 |
535.58 | 5.14 | 5.14 |
444.42 | 3.28 | 3.28 |
438.42 | 3.74 | 3.74 |
585.63 | 4.00 | 4.00 |
469.50 | 3.55 | 3.55 |
483.83 | 4.80 | 4.80 |
512.54 | 4.85 | 4.85 |
525.58 | 4.89 | 4.89 |
457.46 | 3.68 | 3.68 |
482.54 | 3.61 | 3.61 |
474.39 | 4.02 | 4.02 |
526.57 | 4.28 | 4.28 |
527.55 | 4.04 | 4.04 |
483.83 | 4.80 | 4.80 |
420.43 | 3.61 | 3.61 |
502.57 | 5.01 | 5.01 |
470.50 | 4.59 | 4.59 |
562.62 | 4.14 | 4.14 |
445.42 | 4.32 | 4.32 |
557.49 | 4.62 | 4.62 |
583.66 | 5.15 | 5.15 |
456.40 | 3.88 | 3.88 |
500.53 | 3.75 | 3.75 |
539.50 | 4.48 | 4.48 |
447.46 | 3.22 | 3.22 |
403.41 | 3.21 | 3.21 |
445.42 | 4.32 | 4.32 |
479.41 | 4.16 | 4.16 |
565.65 | 4.98 | 4.98 |
461.42 | 4.02 | 4.02 |
558.61 | 3.42 | 3.42 |
456.40 | 3.88 | 3.88 |
557.62 | 4.62 | 4.62 |
499.54 | 4.35 | 4.35 |
461.42 | 4.02 | 4.02 |
488.49 | 4.73 | 4.73 |
438.42 | 3.74 | 3.74 |
479.41 | 4.16 | 4.16 |
569.63 | 4.76 | 4.76 |
472.47 | 3.99 | 3.99 |
474.46 | 4.42 | 4.42 |
479.41 | 4.16 | 4.16 |
439.40 | 3.14 | 3.14 |
448.84 | 3.92 | 3.92 |
445.45 | 3.61 | 3.61 |
474.39 | 4.02 | 4.02 |
483.83 | 4.80 | 4.80 |
428.42 | 3.58 | 3.58 |
548.59 | 4.26 | 4.26 |
456.40 | 3.88 | 3.88 |
465.84 | 4.67 | 4.67 |
533.58 | 4.29 | 4.29 |
604.66 | 3.91 | 3.91 |
503.56 | 4.40 | 4.40 |
527.59 | 5.47 | 5.47 |
463.41 | 4.46 | 4.46 |