Basic Information
ID: ALA3880327
Type: Binding
Description: Displacement of [3H]-diprenorphine from guinea pig kappa opioid receptor expressed in CHOK1 cell membranes
Organism: Cavia porcellus
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA3880327
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.62 | 2.26 | 2.26 |
| 555.69 | 2.26 | 2.26 |
| 440.52 | 3.75 | 3.75 |
| 378.52 | 4.15 | 4.15 |
| 611.68 | 2.96 | 2.96 |
| 414.50 | 4.43 | 4.43 |
| 441.62 | 3.00 | 3.00 |
| 474.69 | 6.49 | 6.49 |
| 557.61 | 1.87 | 1.87 |
| 473.61 | 1.23 | 1.23 |
| 547.65 | 2.26 | 2.26 |
| 527.58 | 2.51 | 2.51 |
| 398.59 | 4.92 | 4.92 |
| 639.66 | 4.35 | 4.35 |
| 476.66 | 5.25 | 5.25 |
| 468.64 | 5.76 | 5.76 |
| 531.65 | 1.34 | 1.34 |
| 595.70 | 4.07 | 4.07 |
| 438.66 | 5.70 | 5.70 |
| 456.58 | 5.46 | 5.46 |
| 456.67 | 4.92 | 4.92 |
| 434.62 | 5.57 | 5.57 |
| 601.57 | 2.16 | 2.16 |
| 428.96 | 3.78 | 3.78 |
| 639.68 | 3.19 | 3.19 |
| 585.57 | 3.18 | 3.18 |
| 462.51 | 4.14 | 4.14 |
| 589.68 | 2.56 | 2.56 |
| 446.64 | 5.71 | 5.71 |
| 629.67 | 2.75 | 2.75 |
| 482.71 | 4.25 | 4.25 |
| 477.67 | 3.17 | 3.17 |
| 462.66 | 3.56 | 3.56 |
| 421.54 | 2.52 | 2.52 |
| 609.61 | 3.69 | 3.69 |
| 392.54 | 4.54 | 4.54 |
| 555.62 | 2.96 | 2.96 |
| 590.71 | 3.18 | 3.18 |
| 441.62 | 3.78 | 3.78 |
| 580.55 | 3.72 | 3.72 |
| 469.63 | 3.77 | 3.77 |
| 448.65 | 5.96 | 5.96 |
| 671.70 | 3.74 | 3.74 |
| 463.57 | 3.14 | 3.14 |
| 559.60 | 2.85 | 2.85 |
| 603.56 | 3.54 | 3.54 |
| 442.60 | 4.38 | 4.38 |
| 434.62 | 5.57 | 5.57 |
| 613.62 | 3.82 | 3.82 |
| 639.63 | 3.05 | 3.05 |
| 563.62 | 3.30 | 3.30 |
| 524.75 | 6.33 | 6.33 |
| 579.62 | 1.92 | 1.92 |
| 482.71 | 5.45 | 5.45 |
| 519.61 | 2.85 | 2.85 |
| 607.62 | 2.50 | 2.50 |
| 400.56 | 3.50 | 3.50 |
| 450.58 | 4.08 | 4.08 |
| 441.62 | 3.29 | 3.29 |
| 456.63 | 4.46 | 4.46 |
| 460.66 | 5.75 | 5.75 |
| 611.68 | 2.61 | 2.61 |
| 543.58 | 1.48 | 1.48 |
| 487.69 | 5.15 | 5.15 |
| 543.58 | 1.48 | 1.48 |
| 510.72 | 5.94 | 5.94 |
| 579.62 | 2.27 | 2.27 |
| 489.68 | 2.95 | 2.95 |
| 454.66 | 3.47 | 3.47 |
| 652.66 | 3.82 | 3.82 |
| 597.66 | 2.57 | 2.57 |
| 567.58 | 2.70 | 2.70 |
| 586.55 | 4.27 | 4.27 |
| 661.67 | 4.41 | 4.41 |
| 469.67 | 3.92 | 3.92 |
| 455.64 | 3.68 | 3.68 |
| 579.62 | 2.27 | 2.27 |
| 589.63 | 2.21 | 2.21 |
| 426.60 | 4.04 | 4.04 |
| 544.57 | 3.44 | 3.44 |
| 493.67 | 6.03 | 6.03 |
| 579.62 | 2.27 | 2.27 |
| 394.52 | 3.12 | 3.12 |
| 468.69 | 4.89 | 4.89 |
| 473.61 | 1.23 | 1.23 |
| 428.57 | 3.99 | 3.99 |
| 520.69 | 5.43 | 5.43 |
| 505.66 | 5.95 | 5.95 |
| 503.71 | 3.34 | 3.34 |
| 577.69 | 4.56 | 4.56 |
| 482.71 | 5.28 | 5.28 |
| 479.64 | 6.36 | 6.36 |
| 599.60 | 3.57 | 3.57 |
| 452.68 | 6.09 | 6.09 |
| 425.62 | 4.31 | 4.31 |
| 418.58 | 4.93 | 4.93 |
| 504.72 | 5.51 | 5.51 |
| 553.55 | 2.66 | 2.66 |
| 585.57 | 3.45 | 3.45 |
| 466.71 | 6.48 | 6.48 |
| 438.59 | 5.32 | 5.32 |
| 453.63 | 3.43 | 3.43 |
| 506.67 | 3.01 | 3.01 |
| 517.76 | 5.68 | 5.68 |
| 527.58 | 2.51 | 2.51 |
| 567.65 | 3.43 | 3.43 |
| 482.71 | 5.45 | 5.45 |
| 557.61 | 1.87 | 1.87 |
| 571.64 | 2.12 | 2.12 |
| 698.70 | 2.49 | 2.49 |
| 585.66 | 2.51 | 2.51 |
| 608.70 | 5.01 | 5.01 |
| 485.67 | 2.90 | 2.90 |
| 627.65 | 4.62 | 4.62 |
| 550.66 | 5.17 | 5.17 |
| 460.66 | 6.10 | 6.10 |
| 498.71 | 3.22 | 3.22 |
| 470.54 | 3.11 | 3.11 |
| 577.64 | 3.69 | 3.69 |
| 620.64 | 3.08 | 3.08 |
| 607.62 | 2.50 | 2.50 |
| 458.51 | 3.88 | 3.88 |
| 436.55 | 4.00 | 4.00 |
| 597.58 | 3.33 | 3.33 |
| 460.66 | 6.10 | 6.10 |
| 615.60 | 2.47 | 2.47 |
| 575.67 | 4.96 | 4.96 |
| 472.53 | 4.27 | 4.27 |
| 635.67 | 3.14 | 3.14 |
| 474.60 | 3.32 | 3.32 |
| 544.78 | 5.08 | 5.08 |
| 615.65 | 2.71 | 2.71 |
| 426.61 | 2.86 | 2.86 |
| 492.59 | 3.45 | 3.45 |
| 525.69 | 2.01 | 2.01 |
| 575.65 | 2.17 | 2.17 |
| 427.59 | 2.90 | 2.90 |
| 553.55 | 2.66 | 2.66 |
| 526.77 | 4.04 | 4.04 |
| 484.68 | 5.40 | 5.40 |
| 616.68 | 3.27 | 3.27 |
| 457.62 | 2.26 | 2.26 |
| 496.69 | 5.40 | 5.40 |
| 553.67 | 4.56 | 4.56 |
| 603.70 | 2.95 | 2.95 |
| 561.65 | 4.57 | 4.57 |
| 526.77 | 4.00 | 4.00 |
| 627.65 | 4.21 | 4.21 |
| 547.64 | 2.95 | 2.95 |
| 484.69 | 2.83 | 2.83 |
| 384.56 | 4.53 | 4.53 |
| 549.59 | 2.91 | 2.91 |
| 435.57 | 2.56 | 2.56 |
| 566.66 | 4.14 | 4.14 |
| 601.57 | 2.16 | 2.16 |
| 449.60 | 2.95 | 2.95 |
| 591.62 | 3.53 | 3.53 |
| 549.59 | 3.17 | 3.17 |
| 565.59 | 2.27 | 2.27 |
| 430.50 | 3.40 | 3.40 |
| 565.59 | 1.88 | 1.88 |
| 569.67 | 3.53 | 3.53 |
| 565.59 | 1.88 | 1.88 |
| 450.58 | 4.38 | 4.38 |
| 412.51 | 3.26 | 3.26 |
| 555.64 | 3.55 | 3.55 |
| 627.68 | 2.32 | 2.32 |
| 550.57 | 3.69 | 3.69 |
| 762.74 | 3.46 | 3.46 |
| 617.73 | 3.20 | 3.20 |
| 635.72 | 4.41 | 4.41 |
| 455.64 | 3.68 | 3.68 |
| 585.66 | 2.50 | 2.50 |
| 454.66 | 4.50 | 4.50 |
| 449.60 | 3.30 | 3.30 |
| 593.69 | 3.53 | 3.53 |
| 561.60 | 3.05 | 3.05 |
| 585.66 | 2.65 | 2.65 |
| 532.69 | 5.34 | 5.34 |
| 475.68 | 5.89 | 5.89 |
| 597.63 | 4.85 | 4.85 |
| 435.57 | 2.91 | 2.91 |
| 541.61 | 2.90 | 2.90 |
| 432.61 | 5.32 | 5.32 |
| 577.64 | 3.54 | 3.54 |
| 585.66 | 2.65 | 2.65 |
| 591.60 | 3.24 | 3.24 |
| 455.69 | 5.88 | 5.88 |
| 543.55 | 3.83 | 3.83 |
| 483.65 | 3.86 | 3.86 |
| 665.65 | 3.59 | 3.59 |
| 483.70 | 4.31 | 4.31 |
| 567.58 | 2.70 | 2.70 |
| 521.70 | 6.23 | 6.23 |
| 527.66 | 6.82 | 6.82 |
| 490.69 | 5.12 | 5.12 |
| 615.65 | 2.71 | 2.71 |
| 441.66 | 5.49 | 5.49 |
| 517.71 | 4.51 | 4.51 |
| 412.51 | 3.26 | 3.26 |
| 426.65 | 5.56 | 5.56 |
| 504.72 | 5.51 | 5.51 |
| 513.56 | 2.12 | 2.12 |
| 441.62 | 3.29 | 3.29 |
| 495.66 | 2.65 | 2.65 |
| 593.64 | 2.66 | 2.66 |