Basic Information
ID: ALA3880355
Type: Binding
Description: Inhibition of TAK1 in human A549 cells assessed as decrease in recombinant human IL-1beta-stimulated IL6 production at 50 uM preincubated for 3 hrs followed by IL-1beta stimulation measured after 18 hrs relative to control
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA3880355
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 294.31 | 2.04 | 2.04 |
| 273.34 | 2.99 | 2.99 |
| 276.30 | 0.61 | 0.61 |
| 309.32 | 2.72 | 2.72 |
| 278.29 | 1.79 | 1.79 |
| 260.30 | 1.63 | 1.63 |
| 216.24 | 1.86 | 1.86 |
| 318.38 | 1.50 | 1.50 |
| 286.21 | 1.40 | 1.40 |
| 280.29 | 2.25 | 2.25 |
| 267.72 | 2.41 | 2.41 |
| 246.27 | 1.25 | 1.25 |
| 242.28 | 2.53 | 2.53 |
| 276.30 | 3.07 | 3.07 |
| 274.32 | 1.58 | 1.58 |
| 322.32 | 2.41 | 2.41 |
| 260.30 | 1.63 | 1.63 |
| 258.28 | 0.83 | 0.83 |
| 274.32 | 1.75 | 1.75 |
| 274.32 | 1.88 | 1.88 |
| 288.35 | 2.14 | 2.14 |
| 288.35 | 2.09 | 2.09 |
| 275.31 | 2.18 | 2.18 |
| 246.27 | 1.24 | 1.24 |
| 289.34 | 2.57 | 2.57 |
| 314.39 | 2.53 | 2.53 |
| 300.36 | 2.28 | 2.28 |
| 318.38 | 1.50 | 1.50 |
| 260.30 | 1.49 | 1.49 |
| 312.30 | 2.17 | 2.17 |
| 294.74 | 2.06 | 2.06 |
| 261.28 | 2.09 | 2.09 |