ID: ALA3880376
Type: Binding
Description: Antagonist activity at recombinant human N-terminal signal peptide/FLAG epitope-tagged Rluc8-fused VIPR2 expressed in HEK293 cells assessed as inhibition of VIP-induced human mVenus-beta-arrestin2 binding preincubated for 5 mins with luciferin, coelenterazine H followed by VIP addition measured after 5 mins by BRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Vasoactive intestinal polypeptide receptor 2(ALA4532)
Document: ALA3879914
Antagonist activity at recombinant human N-terminal signal peptide/FLAG epitope-tagged Rluc8-fused VIPR2 expressed in HEK293 cells assessed as inhibition of VIP-induced human mVenus-beta-arrestin2 binding preincubated for 5 mins with luciferin, coelenterazine H followed by VIP addition measured after 5 mins by BRET assay: 38
Bioactivity
Activity Types for Assay ALA3880376
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
550.68 | 3.21 | 3.21 |
513.06 | 4.03 | 4.03 |
566.68 | 2.77 | 2.77 |
543.09 | 3.66 | 3.66 |
529.06 | 3.00 | 3.00 |
580.70 | 3.12 | 3.12 |
475.57 | 2.50 | 2.50 |
580.70 | 3.43 | 3.43 |
475.57 | 2.50 | 2.50 |
594.73 | 3.77 | 3.77 |
550.68 | 3.80 | 3.80 |
534.68 | 2.84 | 2.84 |
527.09 | 4.69 | 4.69 |
571.14 | 4.65 | 4.65 |
538.67 | 2.40 | 2.40 |
550.68 | 3.21 | 3.21 |
550.68 | 3.21 | 3.21 |
550.72 | 3.86 | 3.86 |
505.64 | 3.42 | 3.42 |
578.61 | 3.25 | 3.25 |
552.65 | 2.12 | 2.12 |
543.09 | 3.66 | 3.66 |
491.57 | 1.51 | 1.51 |
566.68 | 2.77 | 2.77 |
522.67 | 2.91 | 2.91 |
522.67 | 2.97 | 2.97 |
524.64 | 2.36 | 2.36 |
527.09 | 4.42 | 4.42 |
508.64 | 2.66 | 2.66 |
512.60 | 2.49 | 2.49 |
566.68 | 2.77 | 2.77 |
543.09 | 3.66 | 3.66 |
435.50 | 1.62 | 1.62 |
576.76 | 4.40 | 4.40 |
527.09 | 4.42 | 4.42 |
557.11 | 4.00 | 4.00 |
557.11 | 4.31 | 4.31 |
566.72 | 3.53 | 3.53 |
536.69 | 3.30 | 3.30 |
557.11 | 4.31 | 4.31 |
564.70 | 3.86 | 3.86 |
534.68 | 4.24 | 4.24 |
536.69 | 3.47 | 3.47 |
463.56 | 2.40 | 2.40 |
578.73 | 4.20 | 4.20 |
505.64 | 3.42 | 3.42 |
536.65 | 2.55 | 2.55 |
580.70 | 3.43 | 3.43 |
539.61 | 2.26 | 2.26 |
564.70 | 3.86 | 3.86 |
519.62 | 2.22 | 2.22 |
552.69 | 3.14 | 3.14 |
538.62 | 2.08 | 2.08 |
562.61 | 3.37 | 3.37 |
529.06 | 3.00 | 3.00 |
572.71 | 1.75 | 1.75 |
564.70 | 3.55 | 3.55 |