Antagonist activity at recombinant human N-terminal signal peptide/FLAG epitope-tagged Rluc8-fused VIPR2 expressed in HEK293 cells assessed as inhibit...

Basic Information

ID: ALA3880376

Type: Binding

Description: Antagonist activity at recombinant human N-terminal signal peptide/FLAG epitope-tagged Rluc8-fused VIPR2 expressed in HEK293 cells assessed as inhibition of VIP-induced human mVenus-beta-arrestin2 binding preincubated for 5 mins with luciferin, coelenterazine H followed by VIP addition measured after 5 mins by BRET assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target:  Vasoactive intestinal polypeptide receptor 2(ALA4532)

Document:  ALA3879914

Antagonist activity at recombinant human N-terminal signal peptide/FLAG epitope-tagged Rluc8-fused VIPR2 expressed in HEK293 cells assessed as inhibition of VIP-induced human mVenus-beta-arrestin2 binding preincubated for 5 mins with luciferin, coelenterazine H followed by VIP addition measured after 5 mins by BRET assay: 38

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
550.683.213.21
513.064.034.03
566.682.772.77
543.093.663.66
529.063.003.00
580.703.123.12
475.572.502.50
580.703.433.43
475.572.502.50
594.733.773.77
550.683.803.80
534.682.842.84
527.094.694.69
571.144.654.65
538.672.402.40
550.683.213.21
550.683.213.21
550.723.863.86
505.643.423.42
578.613.253.25
552.652.122.12
543.093.663.66
491.571.511.51
566.682.772.77
522.672.912.91
522.672.972.97
524.642.362.36
527.094.424.42
508.642.662.66
512.602.492.49
566.682.772.77
543.093.663.66
435.501.621.62
576.764.404.40
527.094.424.42
557.114.004.00
557.114.314.31
566.723.533.53
536.693.303.30
557.114.314.31
564.703.863.86
534.684.244.24
536.693.473.47
463.562.402.40
578.734.204.20
505.643.423.42
536.652.552.55
580.703.433.43
539.612.262.26
564.703.863.86
519.622.222.22
552.693.143.14
538.622.082.08
562.613.373.37
529.063.003.00
572.711.751.75
564.703.553.55