Basic Information
ID: ALA3880380
Type: Functional
Description: Antagonist activity at human PKR1 expressed in RBL2H3 cells assessed as inhibition of prokineticin1-mediated intracellular calcium release preincubated for 10 mins followed by PK1 addition by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: RBL-2H3
Target: Prokineticin receptor 1(ALA5649)
Document: ALA3879916
Antagonist activity at human PKR1 expressed in RBL2H3 cells assessed as inhibition of prokineticin1-mediated intracellular calcium release preincubated for 10 mins followed by PK1 addition by FLIPR assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3880380
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.90 | 3.44 | 3.44 |
| 383.88 | 3.69 | 3.69 |
| 385.41 | 3.47 | 3.47 |
| 400.48 | 3.74 | 3.74 |
| 406.46 | 3.08 | 3.08 |
| 411.93 | 4.03 | 4.03 |
| 404.92 | 3.69 | 3.69 |
| 458.89 | 4.16 | 4.16 |
| 418.95 | 3.95 | 3.95 |
| 383.88 | 3.85 | 3.85 |
| 401.87 | 3.98 | 3.98 |
| 408.89 | 3.58 | 3.58 |
| 401.87 | 3.98 | 3.98 |
| 401.87 | 3.98 | 3.98 |
| 379.91 | 3.94 | 3.94 |
| 423.92 | 3.09 | 3.09 |
| 397.90 | 3.70 | 3.70 |
| 392.43 | 3.07 | 3.07 |
| 440.45 | 3.69 | 3.69 |
| 418.32 | 4.50 | 4.50 |
| 404.92 | 3.45 | 3.45 |
| 365.89 | 3.55 | 3.55 |
| 418.32 | 4.50 | 4.50 |