Basic Information
ID: ALA3880446
Type: Binding
Description: Inhibition of TACE in human mononuclear cells assessed as inhibition of LPS-induced TNF-alpha production measured after 4 hrs in presence of LPS by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Target: ADAM17(ALA3706)
Document: ALA3880381
Inhibition of TACE in human mononuclear cells assessed as inhibition of LPS-induced TNF-alpha production measured after 4 hrs in presence of LPS by ELISA: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3880446
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 503.40 | 3.23 | 3.23 |
| 454.93 | 2.33 | 2.33 |
| 438.48 | 1.81 | 1.81 |
| 434.51 | 1.98 | 1.98 |
| 452.50 | 2.12 | 2.12 |
| 452.50 | 2.12 | 2.12 |
| 452.50 | 2.12 | 2.12 |
| 472.92 | 2.47 | 2.47 |
| 466.53 | 2.37 | 2.37 |
| 486.95 | 2.71 | 2.71 |
| 466.53 | 2.37 | 2.37 |
| 513.41 | 2.68 | 2.68 |
| 586.76 | 2.98 | 2.98 |
| 490.58 | 1.74 | 1.74 |
| 451.48 | 1.10 | 1.10 |
| 434.51 | 1.98 | 1.98 |
| 489.38 | 2.98 | 2.98 |
| 498.51 | 1.45 | 1.45 |
| 486.95 | 2.71 | 2.71 |
| 456.47 | 1.95 | 1.95 |
| 452.50 | 2.06 | 2.06 |
| 476.56 | 0.63 | 0.63 |
| 451.48 | 1.10 | 1.10 |
| 482.99 | 2.88 | 2.88 |
| 468.96 | 2.64 | 2.64 |
| 494.55 | 1.62 | 1.62 |