Basic Information
ID: ALA3880639
Type: Binding
Description: Inhibition of recombinant human LTC4 synthase expressed in Pichia pastoris using LTA4 as substrate preincubated for 10 mins followed by substrate addition measured after 5 mins by HTRF method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3880639
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 478.98 | 6.59 | 6.59 |
| 528.95 | 5.43 | 5.43 |
| 526.98 | 6.15 | 6.15 |
| 504.46 | 6.03 | 6.03 |
| 488.97 | 6.05 | 6.05 |
| 450.92 | 5.66 | 5.66 |
| 450.49 | 5.32 | 5.32 |
| 500.94 | 5.67 | 5.67 |
| 484.94 | 5.97 | 5.97 |
| 539.03 | 7.13 | 7.13 |
| 551.04 | 7.13 | 7.13 |
| 512.99 | 6.59 | 6.59 |
| 586.93 | 6.74 | 6.74 |
| 500.94 | 5.67 | 5.67 |
| 476.94 | 5.72 | 5.72 |
| 510.98 | 6.35 | 6.35 |
| 538.91 | 6.68 | 6.68 |
| 484.94 | 5.86 | 5.86 |
| 541.00 | 6.45 | 6.45 |
| 464.52 | 5.57 | 5.57 |
| 514.92 | 5.39 | 5.39 |
| 488.90 | 5.80 | 5.80 |
| 510.98 | 6.42 | 6.42 |
| 529.04 | 6.83 | 6.83 |
| 554.91 | 6.56 | 6.56 |
| 541.00 | 6.36 | 6.36 |
| 538.91 | 6.68 | 6.68 |
| 514.97 | 5.87 | 5.87 |
| 538.91 | 6.68 | 6.68 |
| 553.06 | 7.52 | 7.52 |
| 541.00 | 6.45 | 6.45 |
| 558.99 | 6.59 | 6.59 |
| 505.01 | 6.98 | 6.98 |
| 515.91 | 5.57 | 5.57 |
| 559.02 | 6.46 | 6.46 |
| 464.95 | 6.05 | 6.05 |
| 476.96 | 6.20 | 6.20 |
| 514.97 | 6.06 | 6.06 |
| 530.96 | 5.68 | 5.68 |
| 464.91 | 4.79 | 4.79 |
| 476.96 | 6.20 | 6.20 |