Basic Information
ID: ALA3880706
Type: Binding
Description: Inhibition of Cdk4/Cyclin D (unknown origin) using retinoblastoma protein substrate and [gamma32P]ATP incubated for 15 mins by beta plate counter based assay
Format: BAO_0000223
Organism: Homo sapiens
Target: Cyclin-dependent kinase 4/cyclin D1(ALA1907601)
Document: ALA3880393
Inhibition of Cdk4/Cyclin D (unknown origin) using retinoblastoma protein substrate and [gamma32P]ATP incubated for 15 mins by beta plate counter based assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3880706
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 306.37 | 3.65 | 3.65 |
| 404.52 | 3.37 | 3.37 |
| 499.41 | 4.08 | 4.08 |
| 307.36 | 3.05 | 3.05 |
| 494.60 | 3.66 | 3.66 |
| 463.59 | 3.03 | 3.03 |
| 531.46 | 4.22 | 4.22 |
| 390.49 | 3.06 | 3.06 |
| 405.51 | 2.76 | 2.76 |
| 447.54 | 3.09 | 3.09 |
| 386.25 | 3.81 | 3.81 |
| 498.43 | 3.87 | 3.87 |
| 363.43 | 1.67 | 1.67 |
| 484.40 | 3.53 | 3.53 |
| 405.51 | 2.84 | 2.84 |
| 475.60 | 3.74 | 3.74 |
| 479.59 | 2.62 | 2.62 |
| 483.41 | 4.13 | 4.13 |
| 485.39 | 3.95 | 3.95 |
| 363.42 | 3.56 | 3.56 |
| 461.57 | 3.31 | 3.31 |
| 475.60 | 3.74 | 3.74 |
| 449.56 | 2.99 | 2.99 |
| 479.59 | 2.87 | 2.87 |
| 512.46 | 4.30 | 4.30 |
| 448.53 | 3.39 | 3.39 |
| 365.44 | 1.92 | 1.92 |
| 400.28 | 4.12 | 4.12 |
| 461.57 | 3.36 | 3.36 |
| 391.48 | 2.45 | 2.45 |
| 531.40 | 3.37 | 3.37 |
| 434.54 | 3.57 | 3.57 |
| 462.55 | 3.21 | 3.21 |
| 468.99 | 3.26 | 3.26 |
| 433.56 | 4.17 | 4.17 |
| 462.60 | 3.64 | 3.64 |
| 483.02 | 3.57 | 3.57 |
| 469.98 | 2.66 | 2.66 |
| 444.94 | 3.20 | 3.20 |
| 446.56 | 4.24 | 4.24 |
| 518.07 | 4.05 | 4.05 |
| 455.99 | 3.02 | 3.02 |
| 456.98 | 2.55 | 2.55 |
| 451.53 | 1.72 | 1.72 |
| 400.28 | 4.20 | 4.20 |
| 511.47 | 4.91 | 4.91 |
| 455.01 | 3.62 | 3.62 |
| 441.97 | 2.76 | 2.76 |
| 499.06 | 4.09 | 4.09 |
| 440.98 | 3.37 | 3.37 |
| 511.47 | 4.91 | 4.91 |
| 483.41 | 4.80 | 4.80 |
| 445.93 | 2.59 | 2.59 |
| 499.02 | 3.24 | 3.24 |
| 457.97 | 1.95 | 1.95 |
| 500.00 | 2.63 | 2.63 |
| 513.04 | 3.54 | 3.54 |
| 474.61 | 4.35 | 4.35 |
| 399.29 | 4.72 | 4.72 |
| 476.58 | 4.17 | 4.17 |
| 404.52 | 3.45 | 3.45 |
| 484.00 | 2.97 | 2.97 |
| 441.97 | 2.64 | 2.64 |
| 500.05 | 3.49 | 3.49 |
| 478.60 | 3.48 | 3.48 |
| 517.08 | 4.65 | 4.65 |
| 505.85 | 4.57 | 4.57 |
| 442.96 | 2.04 | 2.04 |
| 505.85 | 3.82 | 3.82 |
| 506.84 | 3.22 | 3.22 |
| 450.54 | 3.42 | 3.42 |
| 448.57 | 4.27 | 4.27 |
| 364.45 | 2.53 | 2.53 |
| 385.27 | 4.41 | 4.41 |