Basic Information
ID: ALA3880755
Type: Binding
Description: Antagonist activity at rat alpha1B N-type Ca2+ channel expressed in HEK293 cells assessed as 0.2 Hz current frequency dependent channel blocking for 2 mins in presence of Ba2+ by whole-cell patch clamp assay
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3880755
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 528.62 | 7.16 | 7.16 |
| 528.62 | 7.16 | 7.16 |
| 528.62 | 7.16 | 7.16 |
| 495.07 | 6.80 | 6.80 |
| 478.61 | 6.28 | 6.28 |
| 474.65 | 6.45 | 6.45 |
| 490.65 | 6.15 | 6.15 |
| 520.67 | 6.16 | 6.16 |
| 550.70 | 6.17 | 6.17 |
| 529.51 | 7.45 | 7.45 |
| 529.51 | 7.45 | 7.45 |
| 529.51 | 7.45 | 7.45 |
| 529.51 | 7.45 | 7.45 |
| 488.68 | 6.76 | 6.76 |
| 520.67 | 6.16 | 6.16 |
| 526.63 | 6.74 | 6.74 |
| 504.63 | 5.60 | 5.60 |
| 474.60 | 5.67 | 5.67 |
| 596.62 | 8.18 | 8.18 |
| 523.12 | 6.24 | 6.24 |
| 588.84 | 8.44 | 8.44 |
| 516.73 | 7.44 | 7.44 |
| 558.64 | 7.17 | 7.17 |
| 565.97 | 7.45 | 7.45 |
| 504.63 | 5.87 | 5.87 |
| 536.67 | 5.87 | 5.87 |
| 566.75 | 7.72 | 7.72 |
| 534.66 | 5.88 | 5.88 |
| 565.97 | 7.45 | 7.45 |
| 522.67 | 5.29 | 5.29 |
| 633.08 | 8.18 | 8.18 |
| 474.60 | 6.25 | 6.25 |
| 532.68 | 6.07 | 6.07 |