Basic Information
ID: ALA3880757
Type: Binding
Description: Antagonist activity at alpha1C/alpha2delta/beta1b L-type calcium channel (unknown origin) expressed in HEK293 cells assessed as 0.1 Hz current frequency dependent channel blocking for 2 to 3 mins in presence of Ba2+ by whole-cell patch clamp assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Voltage-dependent L-type calcium channel alpha1C/alpha2delta/beta1b(ALA3988638)
Document: ALA3880396
Antagonist activity at alpha1C/alpha2delta/beta1b L-type calcium channel (unknown origin) expressed in HEK293 cells assessed as 0.1 Hz current frequency dependent channel blocking for 2 to 3 mins in presence of Ba2+ by whole-cell patch clamp assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3880757
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 528.62 | 7.16 | 7.16 |
| 588.84 | 8.44 | 8.44 |
| 558.64 | 7.17 | 7.17 |
| 531.53 | 6.80 | 6.80 |
| 532.68 | 6.07 | 6.07 |
| 541.09 | 5.60 | 5.60 |