Basic Information
ID: ALA3880761
Type: Binding
Description: Inhibition of human alpha1G T-type calcium channel expressed in HEK293 cells assessed as current dependent channel blocking at -110 mV holding potential with pre-pulse at -100 mV for 1 sec prior to test pulse at -40 mV for 50 ms by whole cell patch clamp assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3880761
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 495.07 | 6.80 | 6.80 |
| 520.67 | 6.16 | 6.16 |
| 529.51 | 7.45 | 7.45 |
| 529.51 | 7.45 | 7.45 |
| 529.51 | 7.45 | 7.45 |
| 529.51 | 7.45 | 7.45 |
| 488.68 | 6.76 | 6.76 |
| 458.61 | 5.78 | 5.78 |
| 458.61 | 6.12 | 6.12 |
| 565.97 | 7.45 | 7.45 |
| 566.75 | 7.72 | 7.72 |