Basic Information
ID: ALA3880762
Type: Binding
Description: Inhibition of human alpha1G T-type calcium channel expressed in HEK293 cells assessed as current dependent channel blocking at -110 mV holding potential with pre-pulse at -80 mV for 1 sec prior to test pulse at -40 mV for 50 ms by whole cell patch clamp assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Voltage-gated T-type calcium channel alpha-1G subunit(ALA4641)
Document: ALA3880396
Inhibition of human alpha1G T-type calcium channel expressed in HEK293 cells assessed as current dependent channel blocking at -110 mV holding potential with pre-pulse at -80 mV for 1 sec prior to test pulse at -40 mV for 50 ms by whole cell patch clamp assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3880762
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 495.07 | 6.80 | 6.80 |
| 495.07 | 6.80 | 6.80 |
| 529.51 | 7.45 | 7.45 |