Basic Information
ID: ALA3880924
Type: Binding
Description: Inhibition of human IBAT expressed in CHO cells assessed as reduction in [3H]taurocholic acid uptake incubated for 30 to 60 mins by scintillation counting method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Ileal bile acid transporter(ALA2778)
Document: ALA3880413
Inhibition of human IBAT expressed in CHO cells assessed as reduction in [3H]taurocholic acid uptake incubated for 30 to 60 mins by scintillation counting method: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3880924
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 753.96 | 4.55 | 4.55 |
| 816.03 | 5.99 | 5.99 |
| 851.05 | 4.37 | 4.37 |
| 725.91 | 3.77 | 3.77 |
| 823.00 | 3.59 | 3.59 |
| 920.10 | 3.42 | 3.42 |