Basic Information
ID: ALA3880962
Type: Functional
Description: Antagonist at human NK1 receptor expressed in recombinant BacMam virus infected human U2OS cells assessed as inhibition of substance P-induced intracellular calcium release preincubated for 30 mins followed by substance P addition by Fluo-4 calcium dye-based FLIPR assay
Organism: Homo sapiens
Cell type: U2OS
Activity Charts
Bioactivity
Activity Types for Assay ALA3880962
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 588.57 | 6.10 | 6.10 |
| 638.07 | 7.36 | 7.36 |
| 652.09 | 7.75 | 7.75 |
| 626.06 | 6.99 | 6.99 |
| 625.03 | 6.10 | 6.10 |
| 611.53 | 6.55 | 6.55 |
| 574.54 | 5.54 | 5.54 |
| 588.57 | 6.10 | 6.10 |
| 612.03 | 6.60 | 6.60 |
| 595.49 | 6.55 | 6.55 |
| 639.06 | 6.49 | 6.49 |
| 545.54 | 7.24 | 7.24 |
| 625.03 | 6.10 | 6.10 |
| 638.07 | 7.36 | 7.36 |
| 588.57 | 6.10 | 6.10 |
| 639.06 | 6.49 | 6.49 |
| 626.06 | 6.99 | 6.99 |
| 612.03 | 6.60 | 6.60 |
| 574.54 | 5.54 | 5.54 |
| 652.09 | 7.75 | 7.75 |