Basic Information
ID: ALA3880990
Type: Binding
Description: Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate assessed as decrease in PGE2 production at 10 uM preincubated for 15 mins followed by substrate addition measured after 30 mins by radioimmunoassay relative to control
Organism: Mus musculus
Cell type: J774
Activity Charts
Bioactivity
Activity Types for Assay ALA3880990
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.51 | 3.46 | 3.46 |
| 431.49 | 3.07 | 3.07 |
| 459.59 | 3.66 | 3.66 |
| 473.62 | 4.05 | 4.05 |
| 443.52 | 2.94 | 2.94 |
| 457.55 | 3.33 | 3.33 |
| 458.49 | 3.15 | 3.15 |
| 476.48 | 3.29 | 3.29 |
| 490.51 | 3.68 | 3.68 |
| 476.48 | 3.29 | 3.29 |
| 504.59 | 3.87 | 3.87 |
| 518.61 | 4.26 | 4.26 |
| 488.52 | 3.16 | 3.16 |
| 502.55 | 3.55 | 3.55 |
| 413.50 | 2.93 | 2.93 |
| 431.49 | 3.07 | 3.07 |
| 505.52 | 3.14 | 3.14 |
| 519.55 | 3.53 | 3.53 |
| 435.49 | 3.69 | 3.69 |
| 431.53 | 3.94 | 3.94 |
| 431.53 | 3.94 | 3.94 |
| 444.51 | 3.62 | 3.62 |
| 462.50 | 3.76 | 3.76 |
| 462.50 | 3.76 | 3.76 |
| 480.49 | 3.90 | 3.90 |
| 458.54 | 4.01 | 4.01 |
| 476.53 | 4.15 | 4.15 |
| 476.53 | 4.15 | 4.15 |
| 399.51 | 3.41 | 3.41 |
| 417.50 | 3.55 | 3.55 |
| 417.50 | 3.55 | 3.55 |
| 430.50 | 2.65 | 2.65 |
| 444.53 | 3.04 | 3.04 |
| 533.53 | 2.71 | 2.71 |
| 533.53 | 2.71 | 2.71 |
| 488.54 | 2.49 | 2.49 |
| 491.50 | 2.75 | 2.75 |
| 475.50 | 2.86 | 2.86 |
| 430.50 | 2.65 | 2.65 |
| 444.53 | 3.04 | 3.04 |
| 519.51 | 2.32 | 2.32 |
| 474.51 | 2.10 | 2.10 |
| 504.54 | 4.07 | 4.07 |
| 459.54 | 3.85 | 3.85 |
| 516.57 | 3.94 | 3.94 |
| 532.64 | 4.65 | 4.65 |
| 519.51 | 2.32 | 2.32 |
| 504.54 | 4.07 | 4.07 |
| 487.64 | 4.44 | 4.44 |
| 474.51 | 2.10 | 2.10 |
| 533.52 | 2.73 | 2.73 |
| 471.58 | 3.72 | 3.72 |