Basic Information
ID: ALA3880991
Type: Binding
Description: Inhibition of COX2 in Escherichia coli LPS-stimulated mouse J774 cells using arachidonic acid as substrate assessed as decrease in PGE2 production preincubated for 15 mins followed by substrate addition measured after 30 mins by radioimmunoassay
Organism: Mus musculus
Cell type: J774
Activity Charts
Bioactivity
Activity Types for Assay ALA3880991
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.51 | 3.46 | 3.46 |
| 431.49 | 3.07 | 3.07 |
| 459.59 | 3.66 | 3.66 |
| 473.62 | 4.05 | 4.05 |
| 443.52 | 2.94 | 2.94 |
| 457.55 | 3.33 | 3.33 |
| 458.49 | 3.15 | 3.15 |
| 476.48 | 3.29 | 3.29 |
| 490.51 | 3.68 | 3.68 |
| 476.48 | 3.29 | 3.29 |
| 504.59 | 3.87 | 3.87 |
| 518.61 | 4.26 | 4.26 |
| 488.52 | 3.16 | 3.16 |
| 502.55 | 3.55 | 3.55 |
| 413.50 | 2.93 | 2.93 |
| 431.49 | 3.07 | 3.07 |
| 505.52 | 3.14 | 3.14 |
| 519.55 | 3.53 | 3.53 |
| 435.49 | 3.69 | 3.69 |
| 431.53 | 3.94 | 3.94 |
| 431.53 | 3.94 | 3.94 |
| 444.51 | 3.62 | 3.62 |
| 462.50 | 3.76 | 3.76 |
| 462.50 | 3.76 | 3.76 |
| 480.49 | 3.90 | 3.90 |
| 458.54 | 4.01 | 4.01 |
| 476.53 | 4.15 | 4.15 |
| 476.53 | 4.15 | 4.15 |
| 399.51 | 3.41 | 3.41 |
| 417.50 | 3.55 | 3.55 |
| 417.50 | 3.55 | 3.55 |
| 430.50 | 2.65 | 2.65 |
| 444.53 | 3.04 | 3.04 |
| 533.53 | 2.71 | 2.71 |
| 533.53 | 2.71 | 2.71 |
| 488.54 | 2.49 | 2.49 |
| 491.50 | 2.75 | 2.75 |
| 475.50 | 2.86 | 2.86 |
| 430.50 | 2.65 | 2.65 |
| 444.53 | 3.04 | 3.04 |
| 519.51 | 2.32 | 2.32 |
| 474.51 | 2.10 | 2.10 |
| 504.54 | 4.07 | 4.07 |
| 459.54 | 3.85 | 3.85 |
| 516.57 | 3.94 | 3.94 |
| 532.64 | 4.65 | 4.65 |
| 519.51 | 2.32 | 2.32 |
| 504.54 | 4.07 | 4.07 |
| 487.64 | 4.44 | 4.44 |
| 474.51 | 2.10 | 2.10 |
| 533.52 | 2.73 | 2.73 |
| 471.58 | 3.72 | 3.72 |