Basic Information
ID: ALA3881235
Type: Binding
Description: Selectivity ratio of IC50 for PGD2 receptor in human platelets to IC50 for human EP4 receptor expressed in HEK293 cells by cAMP accumulation assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Unchecked(ALA612545)
Document: ALA3880428
Selectivity ratio of IC50 for PGD2 receptor in human platelets to IC50 for human EP4 receptor expressed in HEK293 cells by cAMP accumulation assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3881235
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.56 | 3.10 | 3.10 |
| 532.64 | 3.28 | 3.28 |
| 500.58 | 2.63 | 2.63 |
| 478.53 | 2.39 | 2.39 |
| 477.58 | 3.73 | 3.73 |
| 468.96 | 3.10 | 3.10 |
| 476.55 | 2.65 | 2.65 |
| 543.60 | 3.29 | 3.29 |
| 545.57 | 2.08 | 2.08 |
| 502.55 | 2.50 | 2.50 |
| 514.40 | 2.61 | 2.61 |
| 465.54 | 3.86 | 3.86 |
| 477.54 | 1.55 | 1.55 |
| 482.99 | 3.49 | 3.49 |
| 459.52 | 2.32 | 2.32 |
| 510.61 | 4.12 | 4.12 |
| 452.96 | 3.27 | 3.27 |
| 516.64 | 4.18 | 4.18 |
| 445.54 | 3.80 | 3.80 |
| 502.55 | 2.50 | 2.50 |
| 568.65 | 2.77 | 2.77 |
| 475.56 | 3.81 | 3.81 |
| 486.95 | 3.24 | 3.24 |
| 561.64 | 2.55 | 2.55 |
| 513.41 | 3.21 | 3.21 |
| 470.49 | 2.73 | 2.73 |
| 544.59 | 2.69 | 2.69 |
| 534.64 | 2.98 | 2.98 |
| 482.99 | 3.49 | 3.49 |
| 573.69 | 3.44 | 3.44 |
| 458.54 | 2.42 | 2.42 |
| 507.57 | 2.63 | 2.63 |
| 479.51 | 2.36 | 2.36 |
| 500.57 | 3.71 | 3.71 |
| 518.62 | 2.97 | 2.97 |
| 593.66 | 3.58 | 3.58 |
| 557.63 | 2.43 | 2.43 |
| 465.96 | 4.07 | 4.07 |
| 557.63 | 2.97 | 2.97 |
| 544.59 | 2.69 | 2.69 |
| 467.97 | 4.16 | 4.16 |
| 526.61 | 4.24 | 4.24 |
| 560.65 | 3.16 | 3.16 |
| 510.61 | 4.12 | 4.12 |
| 558.61 | 3.00 | 3.00 |
| 583.67 | 3.30 | 3.30 |
| 502.51 | 3.47 | 3.47 |
| 448.54 | 2.76 | 2.76 |
| 464.97 | 3.74 | 3.74 |
| 517.63 | 3.57 | 3.57 |
| 482.99 | 3.49 | 3.49 |
| 530.60 | 3.62 | 3.62 |
| 468.96 | 3.10 | 3.10 |
| 517.60 | 2.34 | 2.34 |
| 482.00 | 4.38 | 4.38 |
| 531.63 | 2.59 | 2.59 |
| 500.57 | 3.71 | 3.71 |
| 471.48 | 2.12 | 2.12 |
| 452.50 | 2.59 | 2.59 |
| 469.95 | 2.50 | 2.50 |
| 447.55 | 3.72 | 3.72 |
| 535.62 | 3.41 | 3.41 |
| 500.57 | 3.71 | 3.71 |
| 502.59 | 2.45 | 2.45 |
| 553.64 | 3.70 | 3.70 |
| 516.58 | 2.81 | 2.81 |
| 519.62 | 2.59 | 2.59 |
| 435.50 | 1.84 | 1.84 |
| 540.64 | 4.03 | 4.03 |
| 491.57 | 1.81 | 1.81 |
| 554.63 | 3.10 | 3.10 |
| 513.41 | 3.21 | 3.21 |
| 554.63 | 3.10 | 3.10 |
| 485.03 | 3.81 | 3.81 |
| 515.59 | 3.41 | 3.41 |
| 448.54 | 2.76 | 2.76 |
| 468.96 | 3.10 | 3.10 |
| 553.64 | 3.70 | 3.70 |
| 501.56 | 3.10 | 3.10 |