Basic Information
ID: ALA3881323
Type: Functional
Description: Agonist activity at human recombinant prostacyclin receptor expressed in CHO-K1 cells assessed as induction of cAMP accumulation incubated for 1 hr by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: Prostanoid IP receptor(ALA1995)
Document: ALA3880437
Agonist activity at human recombinant prostacyclin receptor expressed in CHO-K1 cells assessed as induction of cAMP accumulation incubated for 1 hr by HTRF assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3881323
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.92 | 5.52 | 5.52 |
| 449.91 | 5.66 | 5.66 |
| 410.51 | 4.75 | 4.75 |
| 416.45 | 4.40 | 4.40 |
| 427.50 | 4.88 | 4.88 |
| 418.51 | 4.63 | 4.63 |
| 411.50 | 5.18 | 5.18 |
| 451.44 | 5.29 | 5.29 |
| 447.92 | 5.23 | 5.23 |
| 396.49 | 4.44 | 4.44 |
| 397.47 | 4.87 | 4.87 |
| 425.52 | 4.75 | 4.75 |
| 414.48 | 4.58 | 4.58 |
| 399.45 | 3.66 | 3.66 |
| 426.51 | 4.45 | 4.45 |
| 431.92 | 5.52 | 5.52 |
| 435.52 | 5.38 | 5.38 |
| 449.91 | 5.66 | 5.66 |
| 444.50 | 4.59 | 4.59 |
| 430.93 | 5.10 | 5.10 |
| 428.49 | 4.27 | 4.27 |
| 449.91 | 5.66 | 5.66 |
| 432.47 | 4.72 | 4.72 |
| 410.51 | 4.75 | 4.75 |
| 416.45 | 4.40 | 4.40 |
| 539.05 | 4.44 | 4.44 |
| 433.45 | 5.15 | 5.15 |
| 431.92 | 5.52 | 5.52 |
| 488.97 | 4.64 | 4.64 |
| 429.49 | 5.32 | 5.32 |
| 424.54 | 4.33 | 4.33 |
| 415.46 | 5.01 | 5.01 |
| 459.51 | 5.41 | 5.41 |
| 411.50 | 5.18 | 5.18 |
| 429.49 | 5.32 | 5.32 |
| 416.45 | 4.40 | 4.40 |
| 449.91 | 5.66 | 5.66 |
| 427.50 | 4.88 | 4.88 |
| 449.91 | 5.66 | 5.66 |
| 398.46 | 4.26 | 4.26 |
| 427.50 | 4.88 | 4.88 |
| 415.46 | 5.01 | 5.01 |
| 427.50 | 4.88 | 4.88 |
| 416.45 | 4.40 | 4.40 |
| 445.49 | 5.02 | 5.02 |
| 321.37 | 3.14 | 3.14 |
| 415.46 | 5.01 | 5.01 |
| 445.49 | 5.02 | 5.02 |
| 453.58 | 5.53 | 5.53 |
| 411.50 | 5.18 | 5.18 |
| 432.90 | 4.92 | 4.92 |
| 443.52 | 5.62 | 5.62 |
| 416.45 | 4.40 | 4.40 |
| 412.49 | 4.57 | 4.57 |
| 398.46 | 4.26 | 4.26 |
| 459.51 | 5.41 | 5.41 |
| 411.50 | 5.18 | 5.18 |
| 464.48 | 5.46 | 5.46 |
| 410.51 | 4.78 | 4.78 |
| 467.90 | 5.80 | 5.80 |
| 414.48 | 4.58 | 4.58 |
| 397.47 | 4.87 | 4.87 |
| 441.52 | 5.27 | 5.27 |
| 433.45 | 5.15 | 5.15 |
| 440.54 | 4.76 | 4.76 |
| 467.90 | 5.80 | 5.80 |
| 417.44 | 3.80 | 3.80 |
| 429.49 | 5.32 | 5.32 |
| 451.44 | 5.29 | 5.29 |
| 432.47 | 4.72 | 4.72 |
| 434.44 | 4.54 | 4.54 |
| 435.52 | 5.38 | 5.38 |
| 430.93 | 5.10 | 5.10 |
| 432.47 | 4.72 | 4.72 |
| 438.57 | 4.67 | 4.67 |
| 426.51 | 4.45 | 4.45 |
| 431.92 | 5.52 | 5.52 |
| 424.54 | 5.06 | 5.06 |
| 417.53 | 5.24 | 5.24 |
| 424.54 | 5.06 | 5.06 |
| 448.92 | 5.23 | 5.23 |
| 449.91 | 5.66 | 5.66 |
| 415.46 | 5.01 | 5.01 |
| 396.49 | 4.44 | 4.44 |
| 466.46 | 5.28 | 5.28 |
| 433.45 | 5.15 | 5.15 |
| 499.46 | 5.91 | 5.91 |
| 448.92 | 5.23 | 5.23 |
| 414.48 | 4.58 | 4.58 |
| 448.92 | 5.23 | 5.23 |
| 499.46 | 5.91 | 5.91 |
| 427.50 | 4.88 | 4.88 |
| 449.91 | 5.66 | 5.66 |
| 433.45 | 5.15 | 5.15 |
| 447.48 | 5.46 | 5.46 |
| 416.45 | 4.40 | 4.40 |
| 433.45 | 5.15 | 5.15 |
| 433.45 | 5.15 | 5.15 |
| 410.51 | 3.98 | 3.98 |
| 429.49 | 5.32 | 5.32 |