Basic Information
ID: ALA3881373
Type: Binding
Description: Antagonist activity at TLR1/2 in mouse RAW264.7 cells assessed as inhibition of Pam3CSK4-induced receptor activation by measuring NO production after 24 hrs
Organism: Mus musculus
Cell type: RAW264.7
Activity Charts
Bioactivity
Activity Types for Assay ALA3881373
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 220.18 | 1.02 | 1.02 |
| 276.29 | 2.23 | 2.23 |
| 248.19 | 1.01 | 1.01 |
| 388.33 | 1.90 | 1.90 |
| 262.26 | 1.93 | 1.93 |
| 262.22 | 1.10 | 1.10 |
| 222.17 | 1.46 | 1.46 |
| 264.23 | 0.82 | 0.82 |
| 474.59 | 6.18 | 6.18 |
| 278.22 | 1.02 | 1.02 |
| 333.34 | 1.86 | 1.86 |
| 292.24 | 1.11 | 1.11 |
| 262.22 | 1.24 | 1.24 |
| 334.32 | 2.28 | 2.28 |
| 362.38 | 3.06 | 3.06 |
| 306.27 | 1.50 | 1.50 |
| 367.36 | 2.89 | 2.89 |
| 346.29 | 1.68 | 1.68 |
| 320.30 | 1.89 | 1.89 |
| 204.18 | 1.32 | 1.32 |
| 486.39 | 0.93 | 0.93 |
| 374.35 | 1.26 | 1.26 |
| 234.21 | 1.33 | 1.33 |
| 218.21 | 1.63 | 1.63 |
| 418.49 | 4.62 | 4.62 |
| 361.39 | 2.64 | 2.64 |
| 390.43 | 3.84 | 3.84 |