Assay Report Card

Basic Information

ID: ALA3881618

Type: Functional

Description: Antiproliferative activity against taxol-resistant human MES-SA/Dx5 cells expressing MDR1 mRNA and P-gp pretreated with p-gp inhibitor cyclosporinA followed by compound addition

Organism: Homo sapiens

Cell type: MES-SA/Dx5

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
853.923.743.74
336.400.740.74
348.410.910.91
338.411.911.91
468.410.880.88