Basic Information
ID: ALA3881963
Type: Binding
Description: Inhibition of HDAC in human HeLa nuclear extract using Fluor de Lys as substrate after 1 hr by fluorimetric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3881963
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 406.80 | 3.45 | 3.45 |
| 420.83 | 3.84 | 3.84 |
| 434.86 | 4.23 | 4.23 |
| 406.44 | 3.42 | 3.42 |
| 448.88 | 4.62 | 4.62 |
| 420.47 | 3.81 | 3.81 |
| 462.91 | 5.01 | 5.01 |
| 434.50 | 4.20 | 4.20 |
| 569.03 | 6.59 | 6.59 |
| 432.88 | 5.00 | 5.00 |
| 506.96 | 5.03 | 5.03 |
| 489.94 | 4.96 | 4.96 |
| 478.98 | 5.72 | 5.72 |
| 424.50 | 4.09 | 4.09 |
| 442.49 | 4.22 | 4.22 |
| 438.53 | 4.65 | 4.65 |
| 438.53 | 4.65 | 4.65 |
| 462.91 | 5.01 | 5.01 |
| 434.50 | 4.20 | 4.20 |
| 456.52 | 4.79 | 4.79 |
| 472.97 | 5.30 | 5.30 |
| 518.04 | 5.07 | 5.07 |
| 467.50 | 4.76 | 4.76 |
| 476.94 | 5.35 | 5.35 |
| 447.85 | 3.79 | 3.79 |
| 571.73 | 4.61 | 4.61 |
| 466.80 | 5.31 | 5.31 |
| 453.47 | 4.37 | 4.37 |
| 478.55 | 4.21 | 4.21 |
| 557.70 | 4.22 | 4.22 |
| 322.37 | 0.18 | 0.18 |
| 566.96 | 7.02 | 7.02 |
| 553.44 | 3.52 | 3.52 |
| 458.57 | 4.92 | 4.92 |
| 364.36 | 2.25 | 2.25 |
| 593.99 | 6.38 | 6.38 |
| 266.30 | -0.52 | -0.52 |
| 468.55 | 4.65 | 4.65 |
| 433.47 | 3.37 | 3.37 |
| 538.91 | 5.63 | 5.63 |
| 478.55 | 4.21 | 4.21 |
| 500.65 | 5.73 | 5.73 |
| 445.52 | 4.85 | 4.85 |
| 495.67 | 4.05 | 4.05 |
| 494.91 | 5.46 | 5.46 |
| 403.44 | 3.68 | 3.68 |
| 461.52 | 4.15 | 4.15 |
| 552.94 | 6.02 | 6.02 |
| 506.96 | 5.03 | 5.03 |
| 486.62 | 5.34 | 5.34 |
| 573.12 | 4.39 | 4.39 |
| 459.55 | 5.24 | 5.24 |
| 513.65 | 4.20 | 4.20 |
| 587.15 | 4.78 | 4.78 |
| 516.65 | 5.22 | 5.22 |
| 404.83 | 4.22 | 4.22 |
| 565.94 | 5.48 | 5.48 |
| 529.65 | 4.18 | 4.18 |
| 503.40 | 4.85 | 4.85 |
| 447.83 | 2.71 | 2.71 |
| 424.50 | 4.26 | 4.26 |
| 430.51 | 3.78 | 3.78 |
| 585.43 | 2.55 | 2.55 |
| 559.10 | 4.00 | 4.00 |
| 390.80 | 3.83 | 3.83 |
| 537.88 | 4.82 | 4.82 |
| 456.52 | 3.84 | 3.84 |
| 589.01 | 2.59 | 2.59 |
| 510.57 | 4.74 | 4.74 |
| 533.59 | 5.96 | 5.96 |
| 416.49 | 3.39 | 3.39 |
| 556.39 | 3.35 | 3.35 |
| 442.49 | 3.40 | 3.40 |
| 551.91 | 5.21 | 5.21 |
| 538.43 | 2.71 | 2.71 |
| 390.44 | 3.80 | 3.80 |
| 523.73 | 4.83 | 4.83 |
| 440.59 | 4.51 | 4.51 |
| 448.52 | 4.07 | 4.07 |
| 900.52 | 7.54 | 7.54 |
| 526.95 | 5.53 | 5.53 |
| 502.62 | 4.83 | 4.83 |
| 491.57 | 5.77 | 5.77 |
| 460.48 | 4.36 | 4.36 |
| 376.42 | 3.41 | 3.41 |
| 414.82 | 3.81 | 3.81 |
| 512.93 | 4.68 | 4.68 |
| 886.50 | 7.15 | 7.15 |
| 555.73 | 5.37 | 5.37 |
| 557.70 | 4.58 | 4.58 |
| 527.67 | 4.42 | 4.42 |
| 373.42 | 3.92 | 3.92 |
| 438.53 | 4.13 | 4.13 |
| 552.46 | 3.10 | 3.10 |
| 478.48 | 3.19 | 3.19 |
| 450.50 | 4.96 | 4.96 |
| 503.94 | 4.27 | 4.27 |
| 475.89 | 3.49 | 3.49 |
| 458.52 | 4.41 | 4.41 |
| 516.76 | 5.53 | 5.53 |
| 362.75 | 3.05 | 3.05 |
| 398.51 | 3.34 | 3.34 |
| 508.40 | 4.11 | 4.11 |
| 428.85 | 4.20 | 4.20 |
| 472.55 | 4.80 | 4.80 |
| 569.75 | 5.81 | 5.81 |
| 394.48 | 4.25 | 4.25 |
| 523.25 | 3.79 | 3.79 |
| 495.36 | 3.12 | 3.12 |
| 539.41 | 3.13 | 3.13 |
| 426.56 | 4.12 | 4.12 |
| 537.28 | 4.18 | 4.18 |
| 458.57 | 5.28 | 5.28 |
| 555.73 | 5.42 | 5.42 |
| 418.86 | 4.61 | 4.61 |
| 504.59 | 5.93 | 5.93 |
| 613.09 | 6.60 | 6.60 |
| 376.78 | 3.44 | 3.44 |
| 350.42 | 0.91 | 0.91 |
| 509.70 | 4.44 | 4.44 |
| 585.75 | 5.00 | 5.00 |
| 478.56 | 5.53 | 5.53 |
| 472.59 | 5.31 | 5.31 |
| 322.37 | 0.13 | 0.13 |
| 579.96 | 5.99 | 5.99 |
| 539.01 | 6.58 | 6.58 |
| 294.31 | -0.60 | -0.60 |
| 566.96 | 6.41 | 6.41 |
| 604.08 | 7.16 | 7.16 |
| 472.59 | 4.95 | 4.95 |
| 426.50 | 2.64 | 2.64 |
| 450.50 | 4.96 | 4.96 |
| 541.70 | 4.98 | 4.98 |
| 419.44 | 2.98 | 2.98 |
| 524.88 | 5.85 | 5.85 |
| 562.00 | 5.99 | 5.99 |
| 543.67 | 4.57 | 4.57 |
| 447.91 | 2.68 | 2.68 |
| 398.45 | 1.86 | 1.86 |
| 400.41 | 2.28 | 2.28 |
| 392.42 | 3.03 | 3.03 |
| 489.91 | 3.88 | 3.88 |
| 872.47 | 6.76 | 6.76 |
| 428.46 | 3.06 | 3.06 |
| 515.66 | 4.39 | 4.39 |
| 524.94 | 5.15 | 5.15 |
| 509.39 | 3.51 | 3.51 |
| 491.91 | 3.81 | 3.81 |
| 504.63 | 4.57 | 4.57 |
| 535.96 | 4.20 | 4.20 |
| 517.02 | 2.83 | 2.83 |
| 499.62 | 3.81 | 3.81 |
| 579.96 | 6.58 | 6.58 |
| 505.93 | 4.20 | 4.20 |
| 418.86 | 4.39 | 4.39 |
| 504.52 | 3.59 | 3.59 |
| 507.95 | 3.13 | 3.13 |
| 531.04 | 3.22 | 3.22 |
| 485.59 | 3.42 | 3.42 |
| 565.94 | 6.19 | 6.19 |
| 551.30 | 4.57 | 4.57 |
| 392.77 | 3.06 | 3.06 |
| 504.99 | 5.89 | 5.89 |
| 608.02 | 6.65 | 6.65 |
| 473.54 | 3.22 | 3.22 |
| 498.90 | 4.75 | 4.75 |
| 473.58 | 5.63 | 5.63 |
| 511.94 | 4.46 | 4.46 |
| 524.88 | 5.24 | 5.24 |
| 500.60 | 5.58 | 5.58 |
| 496.35 | 1.54 | 1.54 |
| 507.55 | 5.56 | 5.56 |
| 496.89 | 4.94 | 4.94 |
| 928.58 | 8.32 | 8.32 |
| 530.67 | 5.61 | 5.61 |
| 454.56 | 3.42 | 3.42 |
| 517.97 | 4.66 | 4.66 |
| 537.88 | 4.81 | 4.81 |
| 442.49 | 3.45 | 3.45 |
| 516.65 | 5.22 | 5.22 |
| 412.54 | 3.73 | 3.73 |
| 466.51 | 4.73 | 4.73 |
| 334.34 | 2.24 | 2.24 |
| 432.88 | 4.78 | 4.78 |
| 551.91 | 5.09 | 5.09 |
| 482.32 | 1.15 | 1.15 |
| 490.98 | 2.71 | 2.71 |
| 444.50 | 4.02 | 4.02 |
| 481.53 | 5.15 | 5.15 |
| 594.03 | 7.13 | 7.13 |
| 483.30 | 1.57 | 1.57 |
| 545.07 | 3.61 | 3.61 |
| 481.64 | 3.66 | 3.66 |
| 547.09 | 4.27 | 4.27 |
| 529.32 | 0.99 | 0.99 |
| 511.36 | 2.35 | 2.35 |
| 555.40 | 3.95 | 3.95 |
| 506.92 | 5.60 | 5.60 |
| 618.11 | 7.55 | 7.55 |
| 476.94 | 4.88 | 4.88 |
| 294.36 | 0.22 | 0.22 |
| 509.22 | 3.40 | 3.40 |
| 538.91 | 6.24 | 6.24 |
| 583.78 | 6.20 | 6.20 |
| 492.58 | 5.21 | 5.21 |
| 914.55 | 7.93 | 7.93 |
| 533.99 | 4.98 | 4.98 |
| 551.91 | 5.80 | 5.80 |
| 518.62 | 5.61 | 5.61 |
| 527.67 | 4.59 | 4.59 |
| 566.48 | 3.49 | 3.49 |
| 436.47 | 3.60 | 3.60 |
| 608.02 | 6.77 | 6.77 |
| 520.95 | 5.99 | 5.99 |
| 494.91 | 5.14 | 5.14 |
| 525.39 | 2.74 | 2.74 |
| 404.47 | 4.19 | 4.19 |
| 420.47 | 3.90 | 3.90 |
| 463.95 | 4.00 | 4.00 |
| 368.42 | 2.09 | 2.09 |
| 378.39 | 2.64 | 2.64 |
| 450.50 | 3.90 | 3.90 |
| 431.50 | 4.46 | 4.46 |
| 552.94 | 6.63 | 6.63 |
| 542.40 | 3.63 | 3.63 |
| 362.39 | 3.02 | 3.02 |
| 308.34 | -0.21 | -0.21 |
| 632.14 | 7.94 | 7.94 |
| 386.38 | 1.89 | 1.89 |
| 359.39 | 3.36 | 3.36 |
| 599.46 | 2.94 | 2.94 |
| 518.66 | 4.96 | 4.96 |
| 512.93 | 5.14 | 5.14 |
| 408.50 | 4.64 | 4.64 |
| 391.41 | 4.06 | 4.06 |
| 580.01 | 6.74 | 6.74 |
| 579.96 | 5.87 | 5.87 |
| 487.56 | 3.01 | 3.01 |
| 504.02 | 4.68 | 4.68 |
| 459.55 | 5.07 | 5.07 |
| 450.92 | 4.94 | 4.94 |
| 472.59 | 5.67 | 5.67 |
| 480.88 | 5.07 | 5.07 |
| 565.98 | 6.35 | 6.35 |