Basic Information
ID: ALA3882092
Type: Binding
Description: Inhibition of human N-terminal GST-tagged human c-Kit (Thr544 to Val976 residues) expressed in baculovirus expression system assessed as decrease in biotinylated KDR phosphorylation at Tyr996 preincubated for 5 mins followed by substrate addition measured after 30 mins by DELFIA method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3882092
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 518.04 | 5.07 | 5.07 |
| 573.12 | 4.39 | 4.39 |
| 587.15 | 4.78 | 4.78 |
| 579.96 | 5.99 | 5.99 |
| 579.96 | 6.58 | 6.58 |
| 608.02 | 6.65 | 6.65 |
| 547.09 | 4.27 | 4.27 |
| 608.02 | 6.77 | 6.77 |
| 579.96 | 5.87 | 5.87 |
| 504.02 | 4.68 | 4.68 |