Basic Information
ID: ALA3882298
Type: Functional
Description: Antagonist activity at human recombinant M3 receptor expressed in CHO cells assessed as inhibition of oxotremorine-stimulated intracellular calcium release preincubated for 20 mins followed by oxotremorine addition measured every 0.5 to 1 secs for 15 mins by fluo-4AM dye based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Muscarinic acetylcholine receptor M3(ALA245)
Document: ALA3882243
Antagonist activity at human recombinant M3 receptor expressed in CHO cells assessed as inhibition of oxotremorine-stimulated intracellular calcium release preincubated for 20 mins followed by oxotremorine addition measured every 0.5 to 1 secs for 15 mins by fluo-4AM dye based FLIPR assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3882298
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 597.76 | 4.84 | 4.84 |