Apparent lung selectivity index, ratio of ID50 for inhibition of methacholine-induced depressor response in guinea pig administered via nebulization f...

Basic Information

ID: ALA3882301

Type: Functional

Description: Apparent lung selectivity index, ratio of ID50 for inhibition of methacholine-induced depressor response in guinea pig administered via nebulization for 10 mins to ID50 for bronchoprotective activity in Dunkan-Hartley guinea pig assessed as inhibition of acetylcholine-induced bronchoconstriction administered via nebulization for 10 mins

Format: BAO_0000019

Organism: Cavia porcellus

Target:  Cavia porcellus(ALA369)

Document:  ALA3882243

Apparent lung selectivity index, ratio of ID50 for inhibition of methacholine-induced depressor response in guinea pig administered via nebulization for 10 mins to ID50 for bronchoprotective activity in Dunkan-Hartley guinea pig assessed as inhibition of acetylcholine-induced bronchoconstriction administered via nebulization for 10 mins: 38

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
597.764.844.84