Basic Information
ID: ALA3882307
Type: Binding
Description: Inhibition of human full-length N-terminal GST-tagged Aurora B/His-tagged INCENP (803 to 916 residues) using kemptide as substrate and [gamma33P]ATP after 45 mins by liquid scintillation counting method
Format: BAO_0000223
Organism: Homo sapiens
Target: Aurora kinase B/Inner centromere protein(ALA3430907)
Document: ALA3882245
Inhibition of human full-length N-terminal GST-tagged Aurora B/His-tagged INCENP (803 to 916 residues) using kemptide as substrate and [gamma33P]ATP after 45 mins by liquid scintillation counting method: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3882307
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.95 | 5.71 | 5.71 |
| 613.96 | 4.22 | 4.22 |
| 457.94 | 4.64 | 4.64 |
| 577.30 | 6.47 | 6.47 |
| 474.99 | 5.51 | 5.51 |
| 631.46 | 5.75 | 5.75 |
| 481.95 | 5.20 | 5.20 |
| 591.44 | 6.20 | 6.20 |
| 608.49 | 6.94 | 6.94 |
| 485.91 | 3.91 | 3.91 |
| 514.86 | 6.22 | 6.22 |
| 531.96 | 6.07 | 6.07 |
| 558.92 | 4.98 | 4.98 |
| 513.97 | 5.94 | 5.94 |
| 498.95 | 4.53 | 4.53 |
| 425.89 | 5.41 | 5.41 |
| 582.95 | 4.36 | 4.36 |
| 490.99 | 5.30 | 5.30 |
| 532.57 | 6.37 | 6.37 |
| 518.54 | 6.06 | 6.06 |
| 482.95 | 5.53 | 5.53 |
| 444.90 | 3.77 | 3.77 |
| 640.49 | 5.62 | 5.62 |
| 498.41 | 5.71 | 5.71 |
| 648.56 | 6.25 | 6.25 |
| 647.46 | 4.76 | 4.76 |
| 502.47 | 5.59 | 5.59 |
| 624.49 | 5.95 | 5.95 |
| 518.47 | 4.88 | 4.88 |
| 631.51 | 5.00 | 5.00 |
| 484.92 | 4.52 | 4.52 |
| 592.47 | 5.34 | 5.34 |
| 500.99 | 5.89 | 5.89 |
| 443.91 | 4.38 | 4.38 |
| 480.42 | 5.57 | 5.57 |
| 663.46 | 4.43 | 4.43 |
| 471.96 | 4.98 | 4.98 |