Basic Information
ID: ALA3882403
Type: Functional
Description: Agonist activity at human recombinant alpha-2A receptor expressed in PC12 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation measured after 10 mins by cAMP enzyme immunoassay relative to brimonidine
Format: BAO_0000219
Organism: Homo sapiens
Cell type: PC-12
Target: Alpha-2a adrenergic receptor(ALA1867)
Document: ALA3882386
Agonist activity at human recombinant alpha-2A receptor expressed in PC12 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation measured after 10 mins by cAMP enzyme immunoassay relative to brimonidine: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3882403
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 230.10 | 2.36 | 2.36 |
| 200.28 | 3.18 | 3.18 |
| 292.14 | 1.76 | 1.76 |
| 253.72 | 1.72 | 1.72 |
| 167.21 | 0.65 | 0.65 |