Basic Information
ID: ALA3882739
Type: Binding
Description: Inhibition of recombinant human CDS1 using N-terminal biotin-labeled SGLYRSPSMPENLNRPR as substrate in presence of [gamma-33P]-ADP after 3 hrs by scintillation counting method
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase Chk2(ALA2527)
Document: ALA3882721
Inhibition of recombinant human CDS1 using N-terminal biotin-labeled SGLYRSPSMPENLNRPR as substrate in presence of [gamma-33P]-ADP after 3 hrs by scintillation counting method: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3882739
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.34 | 4.72 | 4.72 |
| 372.38 | 3.22 | 3.22 |
| 379.80 | 4.48 | 4.48 |
| 379.42 | 5.27 | 5.27 |
| 363.80 | 4.77 | 4.77 |
| 398.25 | 5.43 | 5.43 |
| 365.41 | 3.67 | 3.67 |
| 363.80 | 4.77 | 4.77 |
| 359.39 | 4.13 | 4.13 |
| 377.83 | 5.08 | 5.08 |
| 431.80 | 5.79 | 5.79 |
| 343.39 | 4.43 | 4.43 |
| 415.35 | 5.28 | 5.28 |
| 357.41 | 4.74 | 4.74 |
| 389.41 | 4.14 | 4.14 |
| 379.87 | 5.13 | 5.13 |
| 374.36 | 4.03 | 4.03 |
| 373.37 | 3.82 | 3.82 |
| 428.49 | 4.60 | 4.60 |
| 461.33 | 4.44 | 4.44 |
| 356.39 | 3.58 | 3.58 |
| 395.87 | 4.15 | 4.15 |
| 411.87 | 3.82 | 3.82 |
| 313.36 | 4.00 | 4.00 |
| 390.83 | 4.23 | 4.23 |
| 347.81 | 4.65 | 4.65 |
| 422.47 | 3.49 | 3.49 |
| 426.89 | 3.78 | 3.78 |
| 361.43 | 4.19 | 4.19 |
| 364.79 | 5.37 | 5.37 |
| 364.79 | 4.17 | 4.17 |
| 398.47 | 3.05 | 3.05 |
| 377.83 | 5.08 | 5.08 |
| 422.47 | 3.14 | 3.14 |
| 467.86 | 5.34 | 5.34 |
| 373.37 | 3.85 | 3.85 |
| 408.25 | 4.88 | 4.88 |
| 424.25 | 4.59 | 4.59 |
| 331.35 | 4.13 | 4.13 |
| 401.42 | 4.14 | 4.14 |
| 348.33 | 4.86 | 4.86 |
| 361.38 | 4.57 | 4.57 |
| 354.37 | 3.99 | 3.99 |
| 377.83 | 5.08 | 5.08 |
| 415.35 | 5.28 | 5.28 |
| 373.48 | 5.04 | 5.04 |
| 461.33 | 4.44 | 4.44 |
| 432.69 | 6.08 | 6.08 |
| 381.79 | 4.91 | 4.91 |
| 380.86 | 4.53 | 4.53 |
| 401.88 | 5.66 | 5.66 |
| 412.28 | 5.74 | 5.74 |
| 412.85 | 4.41 | 4.41 |
| 383.45 | 5.00 | 5.00 |
| 395.82 | 5.22 | 5.22 |
| 442.50 | 4.28 | 4.28 |
| 407.86 | 5.09 | 5.09 |
| 314.35 | 3.39 | 3.39 |
| 408.80 | 4.68 | 4.68 |
| 399.24 | 4.82 | 4.82 |
| 415.47 | 3.79 | 3.79 |
| 466.37 | 4.96 | 4.96 |
| 455.25 | 4.73 | 4.73 |
| 427.51 | 3.66 | 3.66 |
| 330.35 | 3.52 | 3.52 |
| 471.34 | 3.89 | 3.89 |
| 460.44 | 4.15 | 4.15 |
| 431.93 | 4.31 | 4.31 |
| 397.48 | 3.66 | 3.66 |
| 347.35 | 4.26 | 4.26 |
| 397.36 | 5.14 | 5.14 |
| 379.80 | 4.48 | 4.48 |
| 373.41 | 4.39 | 4.39 |
| 347.80 | 4.65 | 4.65 |
| 415.47 | 4.82 | 4.82 |
| 357.41 | 4.68 | 4.68 |
| 433.92 | 4.82 | 4.82 |
| 381.79 | 4.91 | 4.91 |
| 429.42 | 5.38 | 5.38 |
| 348.79 | 5.25 | 5.25 |
| 344.37 | 3.70 | 3.70 |
| 360.44 | 4.18 | 4.18 |
| 397.86 | 5.27 | 5.27 |
| 399.23 | 6.03 | 6.03 |
| 344.37 | 3.82 | 3.82 |
| 440.91 | 3.81 | 3.81 |
| 360.37 | 4.73 | 4.73 |
| 442.48 | 3.56 | 3.56 |
| 397.36 | 5.14 | 5.14 |
| 375.34 | 4.63 | 4.63 |
| 437.44 | 3.04 | 3.04 |
| 405.48 | 4.50 | 4.50 |
| 398.25 | 5.43 | 5.43 |
| 461.33 | 4.44 | 4.44 |
| 477.55 | 2.97 | 2.97 |
| 404.86 | 4.26 | 4.26 |
| 396.86 | 4.75 | 4.75 |
| 423.86 | 4.79 | 4.79 |
| 372.43 | 4.19 | 4.19 |
| 377.83 | 5.04 | 5.04 |